ID   E2ZME3_9FIRM            Unreviewed;      1139 AA.
AC   E2ZME3;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=MutS domain I protein {ECO:0000313|EMBL:EFQ05654.1};
DE   Flags: Fragment;
GN   ORFNames=HMPREF9436_02860 {ECO:0000313|EMBL:EFQ05654.1};
OS   Faecalibacterium cf. prausnitzii KLE1255.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=748224 {ECO:0000313|EMBL:EFQ05654.1, ECO:0000313|Proteomes:UP000006028};
RN   [1] {ECO:0000313|EMBL:EFQ05654.1, ECO:0000313|Proteomes:UP000006028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KLE1255 {ECO:0000313|EMBL:EFQ05654.1,
RC   ECO:0000313|Proteomes:UP000006028};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ05654.1}.
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DR   EMBL; AECU01000210; EFQ05654.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2ZME3; -.
DR   STRING; 748224.HMPREF9436_02860; -.
DR   eggNOG; COG0249; Bacteria.
DR   eggNOG; COG0827; Bacteria.
DR   eggNOG; COG4646; Bacteria.
DR   HOGENOM; CLU_000181_2_0_9; -.
DR   Proteomes; UP000006028; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01624; MutS_I; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840}.
FT   DOMAIN          150..231
FT                   /note="DNA mismatch repair protein MutS-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01624"
FT   NON_TER         1139
FT                   /evidence="ECO:0000313|EMBL:EFQ05654.1"
SQ   SEQUENCE   1139 AA;  127551 MW;  2429D223900E3786 CRC64;
     MAIPTEAEQI ESIDQAESEK SPSAFVLSQA EIENALRRGS NFEDSKLRIW HIYQMQPDRK
     LRAKALAKEY APYGPGGSSH TYLDGSSGWL DHDSKGLTFE HYPDHRKTLL RWDRVEKYID
     LMIQSDRYLS DKERRAIDFP LELNAASAAE YTALKAQHPD TLVGFEAGGN FMFYGEDAAK
     VAKVLNSALF TRETALGEVQ VTGFPPSLWA RKSKELWSAG NDVYLAGLNE DGTHHQTKHL
     HKEDYLPIGS IINMDGRKFR IDGVDFDKGK VSLQDMALAD LRMPVFRQEP LAVVRELYEQ
     EQEVMEHPLP DYKVGDNVIV DLPTRTIEGK IGYVGETDVR IDTSAHGQSW DNEVINKQQF
     EEGLRQNEPN ATRPVRTEKT VAVYPAKENN LPFDIVIQTI STESPTVEAE HSAPEPAGNF
     HITDDHLGEG GAKQKYARNI EAIRTLFKLE EEHRGATAEE QQVLSQYVGW GGLADAFDPG
     KDSWAKEYAE LKGLLSEDEY AAARSSTLNA HYTSPTVIRG IYDAVERMGF RSGNILEPSM
     GVGNFFGMLP DSMAGSRLYG VELDSITGRI AKKLYPQADI TVAGFETTDR RDFYDLAVGN
     VPFGQYKVND KAYNKLGFSI HNYFFAKAID QVRPGGIVAF VTSRYTMDSK DSTARKHMAE
     RADLLGAIRL PNNAFRANAG TDVVSDIIFL QKRDRPADIE PAWVQLGKTE DGFDINQYFV
     DHPEMVLGEL TTESTQYGRE ELTVAPIEGT SLADQLAEAV QHIEGQYTEV EVETPDIADV
     ENEKHILPAD PDVKNFSYTV VDGEVFYREN SVMTQVELSD TAKGRVTGMV ELRQTVNDLI
     DQQLNDYPDE DIQATQAKLN AAYDAFTAKY GLLNDRKNGR LFEQDSSYYL LCSLENLDEQ
     GQLKSKAAMF TKRTIRPERT VTSVDTPSEA LAVSIGEHGK VDLPYMAELL GTPGEYGRIT
     AELSGVIFKD PASDPTDPEA GWQMADEYLS GDVRAKLRMA QFAAETNPEF AVNVDALTKA
     QPRELEASEI DVRLGATWLN PDIIQKFMTE TFQIPYYLRH AVKVRYSPYT AEWRVEGKTA
     TGRGDIISSE TYGTSRANAY KILEETLNLK DVRIYDTIED AEGKPKRVLN KRETMLAQQ
//