ID E3D882_GARV3 Unreviewed; 339 AA.
AC E3D882;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ADP38317.1};
GN OrderedLocusNames=HMPREF0421_20233 {ECO:0000313|EMBL:ADP38317.1};
OS Gardnerella vaginalis (strain ATCC 14019 / 317).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=525284 {ECO:0000313|EMBL:ADP38317.1, ECO:0000313|Proteomes:UP000001453};
RN [1] {ECO:0000313|EMBL:ADP38317.1, ECO:0000313|Proteomes:UP000001453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14019 / 317 {ECO:0000313|Proteomes:UP000001453};
RX PubMed=20865041; DOI=10.1371/journal.pone.0012411;
RA Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G.,
RA Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A.,
RA Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E.,
RA Wilson B.A.;
RT "Comparative genomics of Gardnerella vaginalis strains reveals substantial
RT differences in metabolic and virulence potential.";
RL PLoS ONE 5:E12411-E12411(2010).
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DR EMBL; CP002104; ADP38317.1; -; Genomic_DNA.
DR RefSeq; WP_013399403.1; NC_014644.1.
DR RefSeq; YP_003985340.1; NC_014644.1.
DR AlphaFoldDB; E3D882; -.
DR KEGG; gvg:HMPREF0421_20233; -.
DR PATRIC; fig|525284.18.peg.227; -.
DR HOGENOM; CLU_037628_6_4_11; -.
DR OrthoDB; 3510266at2; -.
DR Proteomes; UP000001453; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 339 AA; 37102 MW; 566126BBB017ECBF CRC64;
MPANIQDVAN EAHVSVSTVS RSFTRPNLVS AITRDKVLAI AEKLNFSISR SAAALKSGRT
LRVALLMSDS IRLWFSASIM QGLNQVLHPA GYDLSIFQIS SSQERAEFFD MLPTRRNADA
VIVCSFDVNK SEVASLKATG VPVLGINCLY PMDCDFDATI NIDDNQGARL MARHLIGLGH
KNIAYIRTNR DVSLHFSVLQ RYHSFIDECK INNITPTEIV APEGLDRISS IVSSLLSNSS
MPTAIACQED GIAIPLMFQL SRSGYSTPGD LSIIGFDDSF YARETGLTTI RQDPVSMAVD
AAKMTLSLIN GDYLDESRRY ITIPAQLIVR SSTSQLDVA
//
