ID E3D905_GARV3 Unreviewed; 385 AA.
AC E3D905;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Penicillin-binding protein dimerization domain protein {ECO:0000313|EMBL:ADP38549.1};
GN OrderedLocusNames=HMPREF0421_20467 {ECO:0000313|EMBL:ADP38549.1};
OS Gardnerella vaginalis (strain ATCC 14019 / 317).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=525284 {ECO:0000313|EMBL:ADP38549.1, ECO:0000313|Proteomes:UP000001453};
RN [1] {ECO:0000313|EMBL:ADP38549.1, ECO:0000313|Proteomes:UP000001453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14019 / 317 {ECO:0000313|Proteomes:UP000001453};
RX PubMed=20865041; DOI=10.1371/journal.pone.0012411;
RA Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G.,
RA Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A.,
RA Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E.,
RA Wilson B.A.;
RT "Comparative genomics of Gardnerella vaginalis strains reveals substantial
RT differences in metabolic and virulence potential.";
RL PLoS ONE 5:E12411-E12411(2010).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP002104; ADP38549.1; -; Genomic_DNA.
DR RefSeq; YP_003985572.1; NC_014644.1.
DR AlphaFoldDB; E3D905; -.
DR KEGG; gvg:HMPREF0421_20467; -.
DR PATRIC; fig|525284.18.peg.465; -.
DR HOGENOM; CLU_717204_0_0_11; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000001453; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR PANTHER; PTHR30627:SF6; BETA-LACTAMASE YBXI-RELATED; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 146..328
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
SQ SEQUENCE 385 AA; 41722 MW; F201D7DBE2739E9C CRC64;
MSRQIKQRFA KYSGKVNGVV NSIKDKVNRT SNSSGFSKTS KSLKDGTSSV FSLLKLIKRK
SQFTRFKKSS TYNANSYEAY GSYNRSAANK TAAMNSTVFA KKCVIVAIIF AFVATCAIVK
LSFIQLINAR STAQAAQAER IRTKPILARR GRILDTNGSV LAQSVERYNI IADPMNAQAF
KPTPCTKQTA GNCHSISGKD VEGTGAVAVA RLLAPILHMS SVEIGGKISG LGRYAVIKRN
VKPSVKRAID KLNLSGCVYA ENSSERVYSS GPILGALIGS VKDAEESSRP EAKGRRGEIG
ESGLELSQDK VLTGTDGYQK YQGNNVGNEK IPGTVSEYKD AVNGNDIKLT IDSDVDWYVK
KSSSRRNEAV QSWMGNCCCS GYSHW
//
