ID E3DAD4_GARV3 Unreviewed; 302 AA.
AC E3DAD4;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Protein-(Glutamine-N5) methyltransferase, release factor-specific {ECO:0000313|EMBL:ADP39028.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:ADP39028.1};
GN Name=prmC {ECO:0000313|EMBL:ADP39028.1};
GN OrderedLocusNames=HMPREF0421_20946 {ECO:0000313|EMBL:ADP39028.1};
OS Gardnerella vaginalis (strain ATCC 14019 / 317).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=525284 {ECO:0000313|EMBL:ADP39028.1, ECO:0000313|Proteomes:UP000001453};
RN [1] {ECO:0000313|EMBL:ADP39028.1, ECO:0000313|Proteomes:UP000001453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14019 / 317 {ECO:0000313|Proteomes:UP000001453};
RX PubMed=20865041; DOI=10.1371/journal.pone.0012411;
RA Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G.,
RA Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A.,
RA Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E.,
RA Wilson B.A.;
RT "Comparative genomics of Gardnerella vaginalis strains reveals substantial
RT differences in metabolic and virulence potential.";
RL PLoS ONE 5:E12411-E12411(2010).
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DR EMBL; CP002104; ADP39028.1; -; Genomic_DNA.
DR RefSeq; WP_013399634.1; NC_014644.1.
DR RefSeq; YP_003986051.1; NC_014644.1.
DR AlphaFoldDB; E3DAD4; -.
DR KEGG; gvg:HMPREF0421_20946; -.
DR PATRIC; fig|525284.18.peg.937; -.
DR HOGENOM; CLU_018398_4_0_11; -.
DR OrthoDB; 9800643at2; -.
DR Proteomes; UP000001453; Chromosome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0102559; F:protein-(glutamine-N5) methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0043412; P:macromolecule modification; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR040758; PrmC_N.
DR InterPro; IPR019874; Release_fac_Glu-N5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR NCBIfam; TIGR03534; RF_mod_PrmC; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF03602; Cons_hypoth95; 1.
DR Pfam; PF17827; PrmC_N; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ADP39028.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ADP39028.1}.
FT DOMAIN 7..80
FT /note="Release factor glutamine methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF17827"
SQ SEQUENCE 302 AA; 33427 MW; B9D17DBB9C4E5BD2 CRC64;
MQEILHILRA SAEKLEDAGV ESAEYDARLL LAHACGVSLA DLNKALILGD FKDFLPNYAS
KYSDFISRRA SREPLQHIIG CATFRYIDLI VGKGVFVPRP ETEVVVQEGL DWIRANNLKN
PIVLDLCAGS GAIGLSVASE VADAQVWAVE KSPKAFEYLQ KNYNKIAEKY NILNRYHAIL
GDATNVNLPE KAAIKEKVDV VITNPPYVPE SQPVEQIEAR DYDPKMALYG GSQDGLLIPQ
KIVKASFAYL RRGGIMIMEH DITQGEALAD YAKNVGFSSA KVKNDLTNRA RFVVCKKEAK
NE
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