ID E3FDL6_STIAD Unreviewed; 388 AA.
AC E3FDL6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN Name=add {ECO:0000313|EMBL:ADO70095.1};
GN OrderedLocusNames=STAUR_2291 {ECO:0000313|EMBL:ADO70095.1};
OS Stigmatella aurantiaca (strain DW4/3-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Archangiaceae; Stigmatella.
OX NCBI_TaxID=378806 {ECO:0000313|EMBL:ADO70095.1, ECO:0000313|Proteomes:UP000001351};
RN [1] {ECO:0000313|EMBL:ADO70095.1, ECO:0000313|Proteomes:UP000001351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DW4/3-1 {ECO:0000313|EMBL:ADO70095.1,
RC ECO:0000313|Proteomes:UP000001351};
RX PubMed=21037205; DOI=10.1093/molbev/msq292;
RA Huntley S., Hamann N., Wegener-Feldbrugge S., Treuner-Lange A., Kube M.,
RA Reinhardt R., Klages S., Muller R., Ronning C.M., Nierman W.C.,
RA Sogaard-Andersen L.;
RT "Comparative genomic analysis of fruiting body formation in Myxococcales.";
RL Mol. Biol. Evol. 28:1083-1097(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR EMBL; CP002271; ADO70095.1; -; Genomic_DNA.
DR AlphaFoldDB; E3FDL6; -.
DR STRING; 378806.STAUR_2291; -.
DR KEGG; sur:STAUR_2291; -.
DR eggNOG; COG1816; Bacteria.
DR HOGENOM; CLU_039228_0_0_7; -.
DR Proteomes; UP000001351; Chromosome.
DR GO; GO:0046936; F:2'-deoxyadenosine deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProtKB-EC.
DR CDD; cd01320; ADA; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01430; aden_deam; 1.
DR PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ADO70095.1}.
FT DOMAIN 43..367
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 42748 MW; EF33F6BF689762F1 CRC64;
MNMASIRDDE LPNATGIPSA ARRTDISPPP ALEVTEELLH ALPKTDLHCH LDGSMRLKTI
LELAEQQKVK LLADTEDGLA QAIHMGQVCK SLDEYLVAFD VTLSVLQTAE ALYRSAYELA
VDAAAENVRY LEVRYSPALH LQKGLKMTTV IDSVLEGLRA AKRETGIKYG VIVCGIRHIN
PQTSMRLAEL SVAYKNRGVI GFDLAGAEAS FPAKDHKDAF QLILKNNVNC TAHAGEAFGP
ESISQAIHYL GAHRIGHGTR LREDGDLLNY VNDHRIPLEV CPTSNVQTGA VTSLAAHPLK
FYFDYGLRVT INTDNRLITD TTVTKELWVA HKELGLSLED LTTILVSGFK SAFLPFREKQ
DLLRSVNQEI ATTLAAFETR PKMVRQPA
//
