ID E3FUM2_STIAD Unreviewed; 296 AA.
AC E3FUM2;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=5'-3' exonuclease family protein {ECO:0000313|EMBL:ADO75905.1};
GN OrderedLocusNames=STAUR_8150 {ECO:0000313|EMBL:ADO75905.1};
OS Stigmatella aurantiaca (strain DW4/3-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Archangiaceae; Stigmatella.
OX NCBI_TaxID=378806 {ECO:0000313|EMBL:ADO75905.1, ECO:0000313|Proteomes:UP000001351};
RN [1] {ECO:0000313|EMBL:ADO75905.1, ECO:0000313|Proteomes:UP000001351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DW4/3-1 {ECO:0000313|EMBL:ADO75905.1,
RC ECO:0000313|Proteomes:UP000001351};
RX PubMed=21037205; DOI=10.1093/molbev/msq292;
RA Huntley S., Hamann N., Wegener-Feldbrugge S., Treuner-Lange A., Kube M.,
RA Reinhardt R., Klages S., Muller R., Ronning C.M., Nierman W.C.,
RA Sogaard-Andersen L.;
RT "Comparative genomic analysis of fruiting body formation in Myxococcales.";
RL Mol. Biol. Evol. 28:1083-1097(2011).
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DR EMBL; CP002271; ADO75905.1; -; Genomic_DNA.
DR RefSeq; WP_013378213.1; NZ_AAMD01000093.1.
DR AlphaFoldDB; E3FUM2; -.
DR STRING; 378806.STAUR_8150; -.
DR KEGG; sur:STAUR_8150; -.
DR eggNOG; COG0258; Bacteria.
DR HOGENOM; CLU_004675_1_0_7; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000001351; Chromosome.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:ADO75905.1};
KW Hydrolase {ECO:0000313|EMBL:ADO75905.1};
KW Nuclease {ECO:0000313|EMBL:ADO75905.1}.
FT DOMAIN 1..264
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 296 AA; 32157 MW; EF7F4DC0FFA5A7A6 CRC64;
MRLHLVDGTY ELFRAHFSPR PGHSAPDGQD VKATVGLMSS LLALLHDKAE AVTHLAVAFD
NPIRSFRNTL FAGYKSDEGV PPELHAQFDL AEEAVRALGV TAWSMKDHEA DDALATAAAR
WAAQVEQVRL LTPDKDLGQC VRGRHVVQVD RRQEKELDEE AVRAKLGVPP ASVPDLLALV
GDEADGIPGL TGFGEKGAAT LLTAYGHLEA IPAEAADWKV RPRGAERLAA TLREHREEAL
LYRRLATLVT DAPLKESLAA LAWKGVPRGP FEALCNRLGV TSLKSRPKRW ADPASL
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