ID E3G4H6_ENTLS Unreviewed; 732 AA.
AC E3G4H6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Ornithine decarboxylase {ECO:0000313|EMBL:ADO49370.1};
DE EC=4.1.1.17 {ECO:0000313|EMBL:ADO49370.1};
GN OrderedLocusNames=Entcl_3124 {ECO:0000313|EMBL:ADO49370.1};
OS Enterobacter lignolyticus (strain SCF1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=701347 {ECO:0000313|EMBL:ADO49370.1, ECO:0000313|Proteomes:UP000006872};
RN [1] {ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|Proteomes:UP000006872};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H.,
RA Hazen T.C., Woyke T.;
RT "Complete sequence of Enterobacter cloacae SCF1.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADO49370.1, ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|EMBL:ADO49370.1,
RC ECO:0000313|Proteomes:UP000006872};
RX PubMed=22180812; DOI=10.4056/sigs.2104875;
RA Deangelis K.M., D'Haeseleer P., Chivian D., Fortney J.L., Khudyakov J.,
RA Simmons B., Woo H., Arkin A.P., Davenport K.W., Goodwin L., Chen A.,
RA Ivanova N., Kyrpides N.C., Mavromatis K., Woyke T., Hazen T.C.;
RT "Complete genome sequence of "Enterobacter lignolyticus" SCF1.";
RL Stand. Genomic Sci. 5:69-85(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
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DR EMBL; CP002272; ADO49370.1; -; Genomic_DNA.
DR RefSeq; WP_013367100.1; NC_014618.1.
DR AlphaFoldDB; E3G4H6; -.
DR STRING; 701347.Entcl_3124; -.
DR KEGG; esc:Entcl_3124; -.
DR eggNOG; COG1982; Bacteria.
DR HOGENOM; CLU_014292_3_0_6; -.
DR Proteomes; UP000006872; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004586; F:ornithine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.40.50.220; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR027568; ODC_inducible.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR027464; Ornithine_deCO2ase_N.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR04301; ODC_inducible; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229:SF1; INDUCIBLE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR PIRSF; PIRSF009393; Orn_decarb; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00703; OKR_DC_1; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ADO49370.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR009393-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006872}.
FT DOMAIN 350..364
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|PROSITE:PS00703"
FT MOD_RES 355
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ SEQUENCE 732 AA; 82249 MW; 02C4752C09D137CC CRC64;
MSELKIAVSR TCPDCFTTQR SIINTCDTHF IDVAAAVLSI EDVECGKLDE IDATGYNLPV
FIAINKEEIV PAEYLSRIQG VFEHDETRND FYGRQLEAAA HKYEVQLRPP FFRALVDYVA
QGNSAFDCPG HQGGEFFRRH PAGNQFVEYF GEALFRSDLC NADVAMGDLL IHEGAPCIAQ
QHAAKVFNAD KTYFVLNGTS SSNKVVLNAL LTPGDLVLFD RNNHKSNHHG ALLQAGATPI
YLETARNPYG FIGGIDAHCF EERYLRELVS EAAPNRAQDA RPFRLAVIQL GTYDGTIYNA
RQVVDKIGHL CDYILFDSAW VGYEQFIPMM ADCSPLLLDL NENDPGILVT QSVHKQQAGF
SQTSQIHKKD SHIKGQQRYV PHKRLNNAFM MHASTSPFYP LFAALDINAK MHEGECGRNM
WMDCVVNGIE TRKLILDNCK HIRPFVPEMV DGKPWQSFAT ADISTDLRFF HFVPGERWHG
FEGYAEHQYF VDPCKLLLTT PGIDAANGEY ENFGVPATIL ANFLRENGVI PEKCDLNSIL
FLLTPAEDMA KLQQLVALLV RFETLLESDA PLADVLPSLY GQHKDRYEGY TLRQLCQEMH
NLYARHNVKQ LQKEMFRKSH FPRVSMNPQD ANYAYLRGQV DLVPLPQAEG RIAAEGALPY
PPGVLCVVPG EIWGGAVLRY FTALEEGINL LPGFAPELQG VYIQEHDGRK QVWCYVINDQ
HAPNALLKGE KL
//
