ID E3G619_ENTLS Unreviewed; 1024 AA.
AC E3G619;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Molybdopterin dinucleotide-binding region {ECO:0000313|EMBL:ADO48400.1};
GN OrderedLocusNames=Entcl_2146 {ECO:0000313|EMBL:ADO48400.1};
OS Enterobacter lignolyticus (strain SCF1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=701347 {ECO:0000313|EMBL:ADO48400.1, ECO:0000313|Proteomes:UP000006872};
RN [1] {ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|Proteomes:UP000006872};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H.,
RA Hazen T.C., Woyke T.;
RT "Complete sequence of Enterobacter cloacae SCF1.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADO48400.1, ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|EMBL:ADO48400.1,
RC ECO:0000313|Proteomes:UP000006872};
RX PubMed=22180812; DOI=10.4056/sigs.2104875;
RA Deangelis K.M., D'Haeseleer P., Chivian D., Fortney J.L., Khudyakov J.,
RA Simmons B., Woo H., Arkin A.P., Davenport K.W., Goodwin L., Chen A.,
RA Ivanova N., Kyrpides N.C., Mavromatis K., Woyke T., Hazen T.C.;
RT "Complete genome sequence of "Enterobacter lignolyticus" SCF1.";
RL Stand. Genomic Sci. 5:69-85(2011).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR EMBL; CP002272; ADO48400.1; -; Genomic_DNA.
DR RefSeq; WP_013366136.1; NC_014618.1.
DR AlphaFoldDB; E3G619; -.
DR STRING; 701347.Entcl_2146; -.
DR KEGG; esc:Entcl_2146; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_008235_0_0_6; -.
DR Proteomes; UP000006872; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02780; MopB_CT_Tetrathionate_Arsenate-R; 1.
DR CDD; cd02758; MopB_Tetrathionate-Ra; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037946; MopB_CT_Tetrathionate.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR041929; Tetrathionate-R_A_N.
DR PANTHER; PTHR43742:SF9; TETRATHIONATE REDUCTASE SUBUNIT A; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006872};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 71..155
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 1024 AA; 111396 MW; E366E5AA36BA8DBF CRC64;
MAKLSRRQWL KIGLAAGGFA AFGLSYRDIA KRAVEGLVNG TSGKITRDRI FGNALAPEAT
ALGPWRASPD QSLSMTQCFG CWTQCGLRVR VDRKTNTVLR IAGNPWHPLS QEHPFDAALP
FAQAMAKLAG ESGLESRSTA CARGATLLES LYSPHRILTP MKRAGKRGEG KWRSISFEQL
IDEVTEGGNL FGEGHVDGLR AIRDLQTPID PAHPAFGPKA NQLLVTNTSD EGRDGFLRRF
AINSFGSKNF GAHGAYCGLS WRAGSGATLG DLDKNPHVKP DWEHVEFALF IGTSPAQSGN
PFKRQARQLA SARLRESFNY VVVAPALPLT TVLADDRGHW LPVKPGTDSA LTMAMIRWII
ENRRYQESYL RIPHPQAMQR RGEKSWTNAS WLVITDDHHP LAGQHLRAAH LAEMDADADD
ALVVDMDGNL VPASRCEQAM LEVNRPLTLK DGSSVTVKSS FQCLKEAAET LTYAQYSAHC
GIAQTQIVAL AQAFTAHGRK AAAIAHGGMM SGNGFYNAWS VMMLNVLLGN LSLEGGVFVG
GGKFNGLTDG PCYNMTQFPG KVAPKGLSIA RSKTAYETSE EFREKQASGR SPWPAKAPWY
PFVAGQLTEL LPSALDGYPY PLKAWISNMT NPLYGVPGLS QTIGERLKDP QRLPLFIAID
AFMNETTALA DYLIPDTHNF ESWGFTAPWA GVASKTTTAR WPIVAPATSR TASGEAVSME
AFCIAVAKRL QLPGFGDRGL SDSQGNPQPL NRAEDYYLRM AANIAFAGQK PLPEASPQDI
AFSGVDHIWP EIARTLKREE ALRVAFLYSR GGRFAPEAAG RQDGTVGAPW AAPLQIWNSE
VAVHRYAMTG ERYSGCPKWY PPRLSDGRAL DEVYPPSDWP MQLMSFKSNL MSSSTTMIAR
LHHVKPSNLV AINPADGARL HLRHGDKVKI TTPGGSVEAQ VSLLMGVMPG VIAVEHGYGH
KEMGARQHWL DGEPLPHQPQ IASGININDL GFQDPTRTVA GTWLDWVTGA SVRQGLPAKI
SKSG
//
