ID E3GCZ0_ENTLS Unreviewed; 277 AA.
AC E3GCZ0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Ferrous iron permease EfeU {ECO:0000256|ARBA:ARBA00021138};
DE AltName: Full=Fe(2+) ion permease EfeU {ECO:0000256|ARBA:ARBA00032812};
DE AltName: Full=Ferrous iron uptake protein {ECO:0000256|ARBA:ARBA00033458};
GN OrderedLocusNames=Entcl_2761 {ECO:0000313|EMBL:ADO49009.1};
OS Enterobacter lignolyticus (strain SCF1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=701347 {ECO:0000313|EMBL:ADO49009.1, ECO:0000313|Proteomes:UP000006872};
RN [1] {ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|Proteomes:UP000006872};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H.,
RA Hazen T.C., Woyke T.;
RT "Complete sequence of Enterobacter cloacae SCF1.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADO49009.1, ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|EMBL:ADO49009.1,
RC ECO:0000313|Proteomes:UP000006872};
RX PubMed=22180812; DOI=10.4056/sigs.2104875;
RA Deangelis K.M., D'Haeseleer P., Chivian D., Fortney J.L., Khudyakov J.,
RA Simmons B., Woo H., Arkin A.P., Davenport K.W., Goodwin L., Chen A.,
RA Ivanova N., Kyrpides N.C., Mavromatis K., Woyke T., Hazen T.C.;
RT "Complete genome sequence of "Enterobacter lignolyticus" SCF1.";
RL Stand. Genomic Sci. 5:69-85(2011).
CC -!- FUNCTION: Uptake of Fe(2+) ions across the membrane.
CC {ECO:0000256|ARBA:ARBA00003776}.
CC -!- SUBUNIT: Part of a ferrous iron transporter composed of EfeU, EfeO and
CC EfeB. {ECO:0000256|ARBA:ARBA00011401}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
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DR EMBL; CP002272; ADO49009.1; -; Genomic_DNA.
DR RefSeq; WP_013366742.1; NC_014618.1.
DR AlphaFoldDB; E3GCZ0; -.
DR STRING; 701347.Entcl_2761; -.
DR KEGG; esc:Entcl_2761; -.
DR eggNOG; COG0672; Bacteria.
DR HOGENOM; CLU_077905_0_0_6; -.
DR Proteomes; UP000006872; Chromosome.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR005217; FTR1-like.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; NF041756; EfeU; 1.
DR NCBIfam; TIGR00145; FTR1 family protein; 1.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF2; PLASMA MEMBRANE IRON PERMEASE; 1.
DR Pfam; PF03239; FTR1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006872};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 277 AA; 30585 MW; ABA78C287D283484 CRC64;
MFVPFLIMLR EGLEAALIVS LIASYLKRTQ RGRWIGVMWV GVFFAAALCL GLGLFINETT
GEFPQKQQEL FEGIVAVIAV FILTWMVFWM RKVSRNVKQQ LEQAVDNALQ KGSSHGWALI
LMVFFAVARE GLESVFFLLA AFQQDLGIWP PLGAMLGLAT AVVLGFLLYW GGVRLNLGAF
FKWTSLFILF VAAGLAAGAI RAFHEAGLWN HFQDVAFDFS NVLSTHTLLG TLLEGILGYQ
EAPSVSEVAM YFIYLIPALV LFAMPPRVAT APSRSAP
//
