ID E3GXR7_METFV Unreviewed; 405 AA.
AC E3GXR7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Molybdenum cofactor synthesis domain protein {ECO:0000313|EMBL:ADP77099.1};
GN OrderedLocusNames=Mfer_0296 {ECO:0000313|EMBL:ADP77099.1};
OS Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanothermaceae; Methanothermus.
OX NCBI_TaxID=523846 {ECO:0000313|EMBL:ADP77099.1, ECO:0000313|Proteomes:UP000002315};
RN [1] {ECO:0000313|EMBL:ADP77099.1, ECO:0000313|Proteomes:UP000002315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43054 / DSM 2088 / JCM 10308 / V24 S
RC {ECO:0000313|Proteomes:UP000002315};
RX PubMed=21304736;
RA Anderson I., Djao O.D., Misra M., Chertkov O., Nolan M., Lucas S.,
RA Lapidus A., Del Rio T.G., Tice H., Cheng J.F., Tapia R., Han C.,
RA Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Brambilla E., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Sikorski J., Spring S., Rohde M.,
RA Eichinger K., Huber H., Wirth R., Goker M., Detter J.C., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Complete genome sequence of Methanothermus fervidus type strain (V24S).";
RL Stand. Genomic Sci. 3:315-324(2010).
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046}.
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DR EMBL; CP002278; ADP77099.1; -; Genomic_DNA.
DR RefSeq; WP_013413377.1; NC_014658.1.
DR AlphaFoldDB; E3GXR7; -.
DR STRING; 523846.Mfer_0296; -.
DR GeneID; 9962011; -.
DR KEGG; mfv:Mfer_0296; -.
DR HOGENOM; CLU_010186_7_2_2; -.
DR OrthoDB; 31371at2157; -.
DR UniPathway; UPA00344; -.
DR Proteomes; UP000002315; Chromosome.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00887; MoeA; 1.
DR Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR Gene3D; 2.40.340.10; MoeA, C-terminal, domain IV; 1.
DR Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR Gene3D; 2.170.190.11; Molybdopterin biosynthesis moea protein, domain 3; 1.
DR InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR InterPro; IPR001453; MoaB/Mog_dom.
DR InterPro; IPR008284; MoCF_biosynth_CS.
DR InterPro; IPR038987; MoeA-like.
DR InterPro; IPR005111; MoeA_C_domain_IV.
DR InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR InterPro; IPR005110; MoeA_linker/N.
DR InterPro; IPR036135; MoeA_linker/N_sf.
DR NCBIfam; TIGR00177; molyb_syn; 1.
DR PANTHER; PTHR10192:SF5; GEPHYRIN; 1.
DR PANTHER; PTHR10192; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN; 1.
DR Pfam; PF00994; MoCF_biosynth; 1.
DR Pfam; PF03454; MoeA_C; 1.
DR Pfam; PF03453; MoeA_N; 1.
DR SMART; SM00852; MoCF_biosynth; 1.
DR SUPFAM; SSF63867; MoeA C-terminal domain-like; 1.
DR SUPFAM; SSF63882; MoeA N-terminal region -like; 1.
DR SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
DR PROSITE; PS01079; MOCF_BIOSYNTHESIS_2; 1.
PE 4: Predicted;
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW Reference proteome {ECO:0000313|Proteomes:UP000002315}.
FT DOMAIN 189..326
FT /note="MoaB/Mog"
FT /evidence="ECO:0000259|SMART:SM00852"
SQ SEQUENCE 405 AA; 44171 MW; 39FF6CE5F5BF0803 CRC64;
MTSEYLQTVE LDKAKKIVEE LFTNFYTTKI EKINIERAHG RVLAENVYSP IDLPPFDRAT
RDGFAVKASD TFGANEENPV KLKCIENIEA GYIPKNTITE GHCARISTGA LIPSGSDAVV
MVEFTEKKNN DILIYKSVYP GQYIAKKGSD IKKGELLLKK NTILSPDKIG ALSAVGIKEI
PVYSKPKIAV ISTGNELIEL SENLKKGKIF DVNSYSIAAS IEECGAKAIN LGIVKDNYED
IKNMILKGLK VADIVVISGG TSAGKGDIVA EVIDDMGEVI LHGIAMKPGK PTIIGKINSK
IIIGLPGYPV SALIVFRVLI APILCKITKA FKLKEKIVRL PISQRFHSTR GRLEFALVSI
ENNKAVPILK DSGAIASLAM SDGYIEIPKN VEIIEKNEKV EVKIF
//
