ID E3GY11_METFV Unreviewed; 650 AA.
AC E3GY11;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=KH-domain/beta-lactamase-domain protein {ECO:0000313|EMBL:ADP77193.1};
GN OrderedLocusNames=Mfer_0391 {ECO:0000313|EMBL:ADP77193.1};
OS Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanothermaceae; Methanothermus.
OX NCBI_TaxID=523846 {ECO:0000313|EMBL:ADP77193.1, ECO:0000313|Proteomes:UP000002315};
RN [1] {ECO:0000313|EMBL:ADP77193.1, ECO:0000313|Proteomes:UP000002315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43054 / DSM 2088 / JCM 10308 / V24 S
RC {ECO:0000313|Proteomes:UP000002315};
RX PubMed=21304736;
RA Anderson I., Djao O.D., Misra M., Chertkov O., Nolan M., Lucas S.,
RA Lapidus A., Del Rio T.G., Tice H., Cheng J.F., Tapia R., Han C.,
RA Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Brambilla E., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Sikorski J., Spring S., Rohde M.,
RA Eichinger K., Huber H., Wirth R., Goker M., Detter J.C., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Complete genome sequence of Methanothermus fervidus type strain (V24S).";
RL Stand. Genomic Sci. 3:315-324(2010).
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DR EMBL; CP002278; ADP77193.1; -; Genomic_DNA.
DR AlphaFoldDB; E3GY11; -.
DR STRING; 523846.Mfer_0391; -.
DR KEGG; mfv:Mfer_0391; -.
DR HOGENOM; CLU_009673_5_1_2; -.
DR Proteomes; UP000002315; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22532; KH-II_CPSF_arch_rpt1; 1.
DR CDD; cd02410; KH-II_CPSF_arch_rpt2; 1.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.30.300.20; -; 1.
DR Gene3D; 3.30.300.230; -; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR019975; aCPSF1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR033769; KH_arc.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR009019; KH_sf_prok-type.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR NCBIfam; TIGR03675; arCOG00543; 1.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF17214; KH_7; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002315};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 111..181
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 207..420
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 436..560
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 650 AA; 73947 MW; BFD5F286EB97B218 CRC64;
MLILLFFKNL FSSDSMTSEI LKEIRKVIAS KIPENVEITK VEFEGPELVV YTKNPEIVAE
DGGLIRTLAK ELKKRIIVRS DASALLDPEK TIEKIKEIVP EEAKITNIYF DDVTGEVIVE
ARKPGLVIGK HGSTSKSIIK HTGWVPKILR TPPIPSKIVE KIRKLLRRES KKRRQILRNL
GCRIHRQPKY ENDWARITAL GGFREVGRSC LYLQTPNSKI LLDCGVNVAA NDEKNAYPYL
NIPEFILDEI EAVVISHAHL DHSGFVPYLY HYGYRGPVYC SAPTRDLMAL LQLDHIDIAE
REGRELPFNA KDVNKCLKHT ITLEYGEVTD ITPDIRLTLH NAGHILGSAI LHLHIGDGQH
NLVYTGDFKY EKTRLLEPAV TDFPRLETLV MESTYGGKED IQPSREMAEK RLIKVIYDTI
KRGGKVLIPV FAVGRAQELM VVLDEYIKSG ILEEIPIFVD GMVWEATAIH TTRPEYLSKT
LSDQIFHYGY NPFTSEIFNK VSSSDERKDV VEGEPCVILS TSGMLAGGNS VEYFKWLCED
EKNTLVFVGY QAEGSLGRRL QKNRRDITFE ENGKMKVYKV KMQIETIEGF SGHSDRKQLM
KYVHNLSPKP EKILVCHGNA YKSLDLASSI YKKYRIETRA PLNLEAVRIY
//
