ID E3HF63_ACHXA Unreviewed; 475 AA.
AC E3HF63;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Bacterial regulatory protein, GntR family protein 62 {ECO:0000313|EMBL:ADP18922.1};
GN OrderedLocusNames=AXYL_05623 {ECO:0000313|EMBL:ADP18922.1};
OS Achromobacter xylosoxidans (strain A8).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=762376 {ECO:0000313|EMBL:ADP18922.1, ECO:0000313|Proteomes:UP000006876};
RN [1] {ECO:0000313|EMBL:ADP18922.1, ECO:0000313|Proteomes:UP000006876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A8 {ECO:0000313|EMBL:ADP18922.1,
RC ECO:0000313|Proteomes:UP000006876};
RX PubMed=21097610; DOI=10.1128/JB.01299-10;
RA Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.;
RT "Complete genome sequence of the haloaromatic acids-degrading bacterium
RT Achromobacter xylosoxidans A8.";
RL J. Bacteriol. 193:791-792(2011).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP002287; ADP18922.1; -; Genomic_DNA.
DR RefSeq; WP_013396221.1; NC_014640.1.
DR AlphaFoldDB; E3HF63; -.
DR STRING; 762376.AXYL_05623; -.
DR KEGG; axy:AXYL_05623; -.
DR PATRIC; fig|762376.5.peg.5631; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_4; -.
DR OrthoDB; 9804020at2; -.
DR Proteomes; UP000006876; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..84
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 475 AA; 51939 MW; DCB4E6EAEB72429A CRC64;
MIDFQPNRAR GRGQAPTLVE QLVAAILRAI EEQTLRPGMS LPSVREFARL YEVSTFTVAS
AYSRLVSLGW LAARPGAGYR VATPDAPARP SQPPSWEPPR LNAGWLLSDI FADHSIPIKS
GCGWLPGEWL NEEGLHMALR HMGRVPAMRI ANYGHPYGYA PLRETIAASL SAQGMEVEAS
QVVLTQGVTH GLDMVIRTLL RPGDTVVVEQ PAYANLLQML RLAGMRAVPV PRTLDGLDCE
ALEAVVARHR PRALVVNTAL QNPSGASISM ANAFRILQAA ERHGLWVVED DISRELAPGV
TPMLAALDGA RRVVYLGGYS KVISPSVRVG YVVAHRDLAR DIARTKMAVG LTSPEIMERI
VHQVIREGRY RAHIARTRER LAEAHAGVAE LMAQHGFEIY GRPQGGLFLW AKVGGPWRER
GANGLAELAL KDGIWLAPGS YFEADEADTP WVRFNVAYSE APALWRFMRN AGAAA
//
