ID E3HX02_ACHXA Unreviewed; 595 AA.
AC E3HX02;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Voltage gated chloride channel family protein 1 {ECO:0000313|EMBL:ADP16356.1};
GN OrderedLocusNames=AXYL_03036 {ECO:0000313|EMBL:ADP16356.1};
OS Achromobacter xylosoxidans (strain A8).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=762376 {ECO:0000313|EMBL:ADP16356.1, ECO:0000313|Proteomes:UP000006876};
RN [1] {ECO:0000313|EMBL:ADP16356.1, ECO:0000313|Proteomes:UP000006876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A8 {ECO:0000313|EMBL:ADP16356.1,
RC ECO:0000313|Proteomes:UP000006876};
RX PubMed=21097610; DOI=10.1128/JB.01299-10;
RA Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.;
RT "Complete genome sequence of the haloaromatic acids-degrading bacterium
RT Achromobacter xylosoxidans A8.";
RL J. Bacteriol. 193:791-792(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002287; ADP16356.1; -; Genomic_DNA.
DR RefSeq; WP_013393671.1; NC_014640.1.
DR AlphaFoldDB; E3HX02; -.
DR STRING; 762376.AXYL_03036; -.
DR KEGG; axy:AXYL_03036; -.
DR PATRIC; fig|762376.5.peg.3054; -.
DR eggNOG; COG0038; Bacteria.
DR eggNOG; COG0517; Bacteria.
DR HOGENOM; CLU_015263_5_0_4; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000006876; Chromosome.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..513
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 522..580
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 595 AA; 62524 MW; A7C6BD31D3592425 CRC64;
MPPTSSSARA ALRLGDFTTD KRVVLLMGLA IPVGLASVAA AWALLRLIAL CTNLAYHHQF
SFEDQPITTG HLGLASVAIP VVGCLIIGLM ARYGSEKIRG HGIPEAMEAI LIGKSRIQPK
VAVLKPVSSA ISIGTGGPFG AEGPIIMTGG AIGSLLAQTI HLDDGERKTL LVAGAAAGMT
AIFATPLAAV LLAVELLLFE WKPRSFLPVA MAALVAAATR AFVLDAGPIF AYAGALSFTP
AHLLACAVVG VLAGLGSGVL TSMVYTAEDL FEKLPLHWMW WPAFGGLVIG IGGLIEPAAL
GVGYDNIRHL LAGDLAFQAV LLLLVVKVII WSVALGSGTS GGVLAPLLIF GGALGALATP
LLPQAAPGFW ALLGMAAMMG GTMRAPLTAT LFAVELTGDM GALLPVLAAC VFAYGVTVLL
LKRSILTEKI ARRGHHISRE YRVDPFDLLR VSQVMTTPVE TLPADWTVAQ AIAHFTTAQP
VHTSYPVLDA QGVVVGEVTR ADTLAWAIDD EQTGRTLGDA LQGRDLVYGH PEELASQIAD
RMALTGAGRV PILDRVNGRL VGIVGRKDLF RSRARRLREE SQRNAYFRRT PSVGR
//
