ID E3JRN0_PUCGT Unreviewed; 1130 AA.
AC E3JRN0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=alpha-mannosidase {ECO:0000256|ARBA:ARBA00012752};
DE EC=3.2.1.24 {ECO:0000256|ARBA:ARBA00012752};
GN ORFNames=PGTG_00725 {ECO:0000313|EMBL:EFP74769.2};
OS Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)
OS (Black stem rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=418459 {ECO:0000313|EMBL:EFP74769.2, ECO:0000313|Proteomes:UP000008783};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CRL 75-36-700-3;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Cuomo C., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA Zeng Q., Kodira C., Yandava C., Alvarado L., O'Leary S., Szabo L., Dean R.,
RA Schein J.;
RT "The Genome Sequence of Puccinia graminis f. sp. tritici Strain CRL 75-36-
RT 700-3.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000008783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRL 75-36-700-3 / race SCCL
RC {ECO:0000313|Proteomes:UP000008783};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS178262; EFP74769.2; -; Genomic_DNA.
DR RefSeq; XP_003307775.2; XM_003307727.2.
DR AlphaFoldDB; E3JRN0; -.
DR STRING; 418459.E3JRN0; -.
DR EnsemblFungi; EFP74769; EFP74769; PGTG_00725.
DR GeneID; 10546625; -.
DR KEGG; pgr:PGTG_00725; -.
DR VEuPathDB; FungiDB:PGTG_00725; -.
DR eggNOG; KOG4342; Eukaryota.
DR HOGENOM; CLU_003442_0_1_1; -.
DR InParanoid; E3JRN0; -.
DR OrthoDB; 2786490at2759; -.
DR Proteomes; UP000008783; Unassembled WGS sequence.
DR GO; GO:0034270; C:Cvt complex; IEA:EnsemblFungi.
DR GO; GO:0000328; C:fungal-type vacuole lumen; IEA:EnsemblFungi.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0004559; F:alpha-mannosidase activity; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019309; P:mannose catabolic process; IEA:EnsemblFungi.
DR GO; GO:0009313; P:oligosaccharide catabolic process; IBA:GO_Central.
DR CDD; cd10812; GH38N_AMII_ScAms1_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008783}.
FT DOMAIN 560..641
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1130 AA; 127786 MW; 45823AF53FCC2EBC CRC64;
MPSTRDEDYP LMENMPRANR FRNVTLGHLK NFIGGDYGSQ NLSSVLYEAR DGSESAVKLE
VWSAPDLSKP SFAEAVRQKY KKISKGFKFG PSWSNHWVKA TLTVPKQYQD RERVLFEFDP
GCEALIFTSE GLPLQGITGG TDSAKRIDFI IPKQSRAFPF QIYIEVSANA LFGVPDEGQL
EVHDDVFFEL AMADIAIPRM DAWHLMWDFQ VISDLTKSVP VTSPICLKAQ TVAMEIMNTF
KPDNLETISA CRKIAEKILG AEWTQKPIYD PKSDWDLEGD SEGVPVFAIG HCHIDTAWEW
PFSVTQQKVA RSWATQVDLI QRYPEYRFVA STAQQYKWLE ELYPQLFSKV RREVENGKFF
VTGGSWVEND TNMPSGEALC RQFLYGQRYF KSRFGKYTDI FWLPDSFGYA SQIPQICRQS
GIPYFFTQKM SWSEFNKFPH STFNWIGIDG TQVLVHMTPV DTYNAQANVD EVLKAITNHK
DLEWSDKTLL VYGNGDGGGG PLAPMIEKLR RIRSASNNSS NSGVPKVTTG PSVSDFYKML
LNKTRNGKDL PTWRGELYLE YHRGTYTSHG SIKRHNRKSE ILMREIEYFA TLASLFREDT
GYEYPKDELD HLWEIVLLCQ FHDVLPGSAI AKVYEDAEKL YAEVAQKGTA LLEAARQSAL
YGSQAVDVVT ASSNRGGNVV GLNTLSFPRQ EILRVPLEIY DGRSAFSASK TDEDSVFVIA
KDATGNGLIE LESLSHLQEH IQLATASVGR DVKTGEVCYF LANKALTVQI SSQGRIVSIV
DTELGRELIL SGQSSGFVMY QDQPLTYDAW NADIFHLDTK EIIDAINVKV VEPKGLRASI
VVECATISLD AVPGSLKKDA LSLVRFETTI DWHEQHKFLK FEVPLDINSD QATYEIQYGV
LQRPTHKNTT WDAAKFEVCG HRFADLSEFG YGVALLNDCK YGYACEGSYL RLSLLRASTS
PDPRQDQGMH KMRFGILPHR GHFLESDVPQ VAMAFNNPIH LRYAPRNISS RNLLAPVTEI
FKLDGLGARN VILDTVKRGE DDTFGFHSRK PVRTVIVRLY EAFGGRANVH LVTLVKAQEV
FIVDVLEREL EKVELKNHQQ SITDDQEPYK QVVELNFKPF QFISLKFILS
//
