ID E3L4C9_PUCGT Unreviewed; 628 AA.
AC E3L4C9;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=PGTG_17360 {ECO:0000313|EMBL:EFP91404.1};
OS Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)
OS (Black stem rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=418459 {ECO:0000313|EMBL:EFP91404.1, ECO:0000313|Proteomes:UP000008783};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CRL 75-36-700-3;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Cuomo C., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA Zeng Q., Kodira C., Yandava C., Alvarado L., O'Leary S., Szabo L., Dean R.,
RA Schein J.;
RT "The Genome Sequence of Puccinia graminis f. sp. tritici Strain CRL 75-36-
RT 700-3.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000008783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRL 75-36-700-3 / race SCCL
RC {ECO:0000313|Proteomes:UP000008783};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; DS178346; EFP91404.1; -; Genomic_DNA.
DR RefSeq; XP_003335823.1; XM_003335775.1.
DR AlphaFoldDB; E3L4C9; -.
DR STRING; 418459.E3L4C9; -.
DR EnsemblFungi; EFP91404; EFP91404; PGTG_17360.
DR GeneID; 10529318; -.
DR KEGG; pgr:PGTG_17360; -.
DR VEuPathDB; FungiDB:PGTG_17360; -.
DR eggNOG; KOG0305; Eukaryota.
DR HOGENOM; CLU_014831_4_1_1; -.
DR InParanoid; E3L4C9; -.
DR OMA; WSKNTDE; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000008783; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IBA:GO_Central.
DR GO; GO:0030332; F:cyclin binding; IEA:EnsemblFungi.
DR GO; GO:1990757; F:ubiquitin ligase activator activity; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:1902426; P:deactivation of mitotic spindle assembly checkpoint; IEA:EnsemblFungi.
DR GO; GO:0010697; P:negative regulation of mitotic spindle pole body separation; IEA:EnsemblFungi.
DR GO; GO:1905786; P:positive regulation of anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:0120151; P:positive regulation of mitotic actomyosin contractile ring disassembly; IEA:EnsemblFungi.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF1; FIZZY-RELATED PROTEIN HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008783};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 285..346
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 290..331
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 373..414
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 509..540
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 68378 MW; BBD5BFECD3B87059 CRC64;
MSLIDNPIAG PSHQRAATTT TTTTTTTTNT SKTRQRQHSS TLESPLHLLD DPFNPSRLSS
IIKPTRPRPA NRSPSSPSKK RHYGDRFIPT RGDGIDLSTS FQLMPDGPST PTRAGNGSKK
TVVAAVTDLE KDEARRTFTN LLKAETFGSD PSEMPHFIHH SSPTHSRQAS TVPNSSPGTP
RRSTATKLFN YSSPSRKESA NVLDSPTHPR YSTTPIKQES QRLLLSPRKP TRALSKVPFK
VLDAPDLADD YYLNLVDWSS TNVLAVGLGS QVYLWSAATS AVTRLVDVAV PGSSDHTTSL
SWIGKGNILA IGTDSGKTHI WDTQVGKRIR TMEGHESRIG CMDWNEYILS TGSRDRSIVH
RDVRAADHWL SRINVHKQEV CGLKWNVNTN QLASGGNDNR LLIWESKASN ALPLFRFNEH
TAAIKALAWS PHQNGLLASG GGSADKRIRF WNTINGTLLN EIDTGSQVCS LKWSKNSNEL
VSTHGFSPGP IQNQVCLWKY PSMQQIATLS GHTYRVLYLA MSPDGETIVT GAGDETLRFW
RAFPKKKSSS SSASPSTTTT TTGTTSGSST MGFESNGNNN TLLAGRGSPI VNHFGAANAN
PSLSPSPIFN PGIHHPPGNF LNLFAQIR
//
