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Database: UniProt
Entry: E3LAG4_PUCGT
LinkDB: E3LAG4_PUCGT
Original site: E3LAG4_PUCGT 
ID   E3LAG4_PUCGT            Unreviewed;      1431 AA.
AC   E3LAG4;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 2.
DT   31-JUL-2019, entry version 49.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFP93539.2};
GN   ORFNames=PGTG_19535 {ECO:0000313|EMBL:EFP93539.2};
OS   Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)
OS   (Black stem rust fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX   NCBI_TaxID=418459 {ECO:0000313|EMBL:EFP93539.2, ECO:0000313|Proteomes:UP000008783};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CRL 75-36-700-3;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Mauceli E.,
RA   Brockman W., Young S., LaButti K., Sykes S., DeCaprio D., Crawford M.,
RA   Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA   Larson L., White J., Zeng Q., Kodira C., Yandava C., Alvarado L.,
RA   O'Leary S., Szabo L., Dean R., Schein J.;
RT   "The Genome Sequence of Puccinia graminis f. sp. tritici Strain CRL
RT   75-36-700-3.";
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000008783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRL 75-36-700-3 / race SCCL
RC   {ECO:0000313|Proteomes:UP000008783};
RX   PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA   Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA   Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J.,
RA   Cantarel B.L., Chiu R., Coutinho P.M., Feau N., Field M., Frey P.,
RA   Gelhaye E., Goldberg J., Grabherr M.G., Kodira C.D., Kohler A.,
RA   Kuees U., Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E.,
RA   Murat C., Pangilinan J.L., Park R., Pearson M., Quesneville H.,
RA   Rouhier N., Sakthikumar S., Salamov A.A., Schmutz J., Selles B.,
RA   Shapiro H., Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y.,
RA   Rouze P., Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA   Grigoriev I.V., Szabo L.J., Martin F.;
RT   "Obligate biotrophy features unraveled by the genomic analysis of rust
RT   fungi.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC   -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC       {ECO:0000256|PROSITE-ProRule:PRU00657}.
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DR   EMBL; DS178397; EFP93539.2; -; Genomic_DNA.
DR   RefSeq; XP_003337958.2; XM_003337910.2.
DR   EnsemblFungi; EFP93539; EFP93539; PGTG_19535.
DR   GeneID; 10543654; -.
DR   KEGG; pgr:PGTG_19535; -.
DR   EuPathDB; FungiDB:PGTG_19535; -.
DR   InParanoid; E3LAG4; -.
DR   KO; K11592; -.
DR   OrthoDB; 1337630at2759; -.
DR   Proteomes; UP000008783; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016442; C:RISC complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004525; F:ribonuclease III activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030422; P:production of siRNA involved in RNA interference; IBA:GO_Central.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 2.
DR   Gene3D; 3.30.160.380; -; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR038248; Dicer_dimer_sf.
DR   InterPro; IPR005034; Dicer_dimerisation_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF03368; Dicer_dimer; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00636; Ribonuclease_3; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS51327; DICER_DSRBF; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008783};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008783};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
FT   DOMAIN       28    209       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      346    528       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   DOMAIN      540    635       Dicer dsRNA-binding fold.
FT                                {ECO:0000259|PROSITE:PS51327}.
FT   DOMAIN      946   1067       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1113   1265       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   REGION     1394   1431       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      198    218       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1431 AA;  161360 MW;  2B0AD4FFA0AA131D CRC64;
     MDTKNPGPTG GLHRPDLIKI PRLYQTELLE EAKKRNIIIR ADTGTGKTIV AVNLIAWTAV
     KTKAKNKNHQ IQAFLVPTRP LAHQQAEYIQ KHCTLRIKAY TGDLQPELWN IRKWHSELNE
     VDVLVSTAQI FYDLISKGYW KLEDVSLLIF DEAHHCRKNH VYNQIMRSHY HRLAKDSTVR
     LPKILGLTAS PIWNFKDLEK AESDIKSLQS ALAAQIYEVK KHTEDVCRHN FKPNEQVVYF
     EPAPDFQQLP HPPWDQINKL LSLHASPKMI AAVESVSLDL GTYAYSLAVL DWLKSLLTIG
     GSNQLMSGRL VDPNYQERIQ SLIKEVEKLV DIDDIPENQL SSKVIALYKI LVNYKEKDDH
     NNFLCIVFVE RRQHAQLLPI LLERNVQLKD FLRPAALTGH GSGNENDLIG IKMDSRTQNR
     TVAKFRTGEH NLTIATSVAE EGLDFRSCRV VIRFDLITTW KGYIQSRGRA RARESDYIVM
     LPTGTANKYL AFSGKEEQLK AALYDRPQDE LIEDGEEEST PQLICQLADG KESILTYSAA
     TSLLNDVCQL IPPDEFLPVV APEYEMMELG ERFKCRVTLP PMAALPPSRR TFTGLEMGTK
     NGAKRSAAFE ACKVLRELGV LNEHFLPQRE DKAAQVRDAD GREIETTQLA DKVEAIISNI
     YGDFRTSSEV WLHKLSFPDD SPAGFSTMGL LCARHLTIPD DLQLFDHDPV SRPLSVKIKH
     SKKVEWEQDD APFNLQRLER FTLLVMQVAV NRKPYEGKLY FLVAPLLNDA IEIDWNLVDT
     PMIPLSEAAD SSRYQCTIVP SRRPRFRIFD TCESAGDLCA ASPPSRVPAC PSMQHFCKKI
     AKFHNLGHFY KTCYDLEDEH LKGDFVYLQT TFQVYNNLLQ SVSTLAHPYR TLLPLKLCQG
     THIPRTIWKV FSYLPSLTRL LHDSIQATAL FMRLDFPMTL LPRGIQALTP PGVGVPWDYQ
     TLETVGDAFL KLATSVHVYL SHLRKGEGDM SHVRSKSVDN DYLRRKAIQA NLPSSILGQR
     FRTDRFRDAQ TEDGKELPNG NFSRNVPRRV LSDVVEALLG AGFLTGGIEL GLKIGTALDL
     CFGGTTPWNE RTLNIAFEGT AHDKLASSIL LKCQALEEKI GYVFKEKLLL VQALTHRSAN
     SFMTNCYERE EWLGDAVVDM WIVQHAYKRF DNATAEELTL ARAKLVSNGS LGFLAIKKLG
     LHKVIMHKSE SFEQACVEAI KAIEPFTSIE EFFSNLENLF VVFDPPKILN DVLEAIVGAV
     FIDSRFDLPT VYRTIDKIFE DVTPGLSRIV ARDPLSTMLR LRDQYQCAEL RRVSTTIKEP
     NPEGEDKDPI SVRVCRIELH GQEIASGRHA SSASVAEQRA SLAALKVLQD PSGDSPAPKS
     AWLGCQCKAR AVSTTAVASS TPAAENKEEI QKEEGSHASQ DLPRQMSHLH M
//
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