ID E3LCN3_CAERE Unreviewed; 1585 AA.
AC E3LCN3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=CRE-KLP-4 protein {ECO:0000313|EMBL:EFO82830.1};
GN Name=Cre-klp-4 {ECO:0000313|EMBL:EFO82830.1};
GN ORFNames=CRE_00428 {ECO:0000313|EMBL:EFO82830.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; DS268407; EFO82830.1; -; Genomic_DNA.
DR RefSeq; XP_003118232.1; XM_003118184.1.
DR STRING; 31234.E3LCN3; -.
DR EnsemblMetazoa; CRE00428.1; CRE00428.1; WBGene00052031.
DR eggNOG; KOG0241; Eukaryota.
DR HOGENOM; CLU_001485_29_2_1; -.
DR InParanoid; E3LCN3; -.
DR OMA; MAIQTEH; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IEA:EnsemblMetazoa.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:EnsemblMetazoa.
DR GO; GO:0043025; C:neuronal cell body; IEA:EnsemblMetazoa.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 2.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 9..347
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 474..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1368..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1531..1550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 362..406
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 474..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 99..106
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1585 AA; 177899 MW; C5E521093ACD826F CRC64;
MIGPDEESAV KVAIRVRPFN KRELDLKTKS VVKIHKEQCI LNHPVEEKNS KTFTFDHSFC
STDPRSYDFA SQETVCYHLG SGVVENAFSG YNACIFAYGQ TGSGKSYTMM GTPDQPGIIP
RVCNDIFTRI HETSNATLSF KIEVSYMEIY NERVRDLLDP KKSSKALKVR EHKILGPMVD
GLSILAVNSF EQISNLLEEG NKSRTVAATN MNAESSRSHA VFSLIVTQTL HDLENGFSGE
KVAKISLVDL AGSERAGKTG AVGKRLEEGG NINKSLTTLG MVISALAERN AKKDKFIPYR
DSVLTWLLKD SLGGNSRTVM IATLSPAADN YEETLSTLRY ADRAKKIVNH AIINEDPNAR
VIRELREEVE TLRMQITQTK KEHAETEELR ERLAESERLV AQMNKSWEER LKETDTLNKE
RQKDLAEIGI SIESSGIKVE KDRFYLVNMN ADPSLNELLV YYINGSAIIG NSEELETSRD
SGLSMSSNDS SKKDDEKGKQ SVHFCFEVRN RVTERTSIVL RGLGIMRRHA KLTIDEYGGR
MRLFVAPMSS ECRICVNGKQ ITDRTLLRNG NRMLVGMNHF FKVNCPKVMD MEQSIMEDST
MFDYNDAWHE VNDANPISSA VDQYMESVTL KHQEDKKAAL EQQYEAFEKY IQSLTAGGFT
PSTPMTPGFG LPTPITTPTG LPPFPFPTNP KQSVKSKFFY WAQRKEEMFA ESLKRLKADV
IHANALVREA NMISKELNKK PKRQTTYDVT LQIPASNLRP IKIKAGQFVC EPVIVVRREG
MSGSQFWTVS QLESRLVDMR DTYNDMLNGY SRASESLNGT PNASPMKTAG IPMNECSSLV
IDPFFESQEH HNLVGVANVF LEVLFHDLRL DYQRKLIEVI FLKVPIISQQ GEVAGRLHVQ
IFRVVTQEEI DNQTSSGPES LLGKTITCRV RIKRASGLPE KLSNFVFCQY SFFNISELLV
VAPANEAANH SSCATTVIFE HQKDFNVMVT EEFMEYVRDD ALSIEVWGHR ICGHPEERVL
DTDEKCKSLQ NRWMEVTRRL EMWTEVRELN DNGEWTSVEV RSADDVATGG IYQLKQGQQR
RLVVGVNVAA PDGLPISIDS ITSVSIGAIM AVKPNNSKSI DSYQEEDLDK IRKQWSHALK
SRQFYLQHQL DTLSAKSGKS EAELDREHSL MGQWVALTEE RTAVECPAPN SCIPGAPCDW
IAPEGVERHI PVLFLDLNSD DMTGEMTSDE NVPRVAGLHS MLPLEPEGNL LLLPIHKYDD
KDHVATCSWD SSVHDTPALN VPTNSNDRIY AIVKIMVRLS HPCPMHIVLR KRICLQIYKK
PSLTEKFFKK MLGTETIHRT SLYYDVVAHI PKSSQDMEDR SSLAMMAAKD TSQDEQGGGS
SRSSTSSTES QHQQQTLNYI EAYTKSIQAV ESMLKLDRLR QEVAITNMLT KKERLQRIQN
FGLPMHSLRM NRAVSLPNAI SSAGQISGME KRSDTPMSIS SSNSMVTSII SPYNDKLTGI
IEETNSLKIE TAPTRSSTVP ETMCFSAAKR MSPTEDVKNG NEESTPSRSA NAMSMGVKLC
LPLENNNQFA SKKLQNGDLV DLKIN
//
