ID E3LEA0_CAERE Unreviewed; 577 AA.
AC E3LEA0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=CRE-IFA-4 protein {ECO:0000313|EMBL:EFO83062.1};
GN Name=Cre-ifa-4 {ECO:0000313|EMBL:EFO83062.1};
GN ORFNames=CRE_00280 {ECO:0000313|EMBL:EFO83062.1}, GCK72_024332
GN {ECO:0000313|EMBL:KAF1747866.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFO83062.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|EMBL:EFO83062.1};
RG The Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF1747866.1, ECO:0000313|Proteomes:UP000483820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX506 {ECO:0000313|EMBL:KAF1747866.1,
RC ECO:0000313|Proteomes:UP000483820};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KAF1747866.1};
RA Teterina A.A., Willis J.H., Phillips P.C.;
RT "Chromosome-level assembly of the Caenorhabditis remanei genome.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|PIRNR:PIRNR005546, ECO:0000256|RuleBase:RU000685}.
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DR EMBL; DS268407; EFO83062.1; -; Genomic_DNA.
DR EMBL; WUAV01000006; KAF1747866.1; -; Genomic_DNA.
DR RefSeq; XP_003118464.1; XM_003118416.1.
DR AlphaFoldDB; E3LEA0; -.
DR STRING; 31234.E3LEA0; -.
DR EnsemblMetazoa; CRE00280.1; CRE00280.1; WBGene00051767.
DR GeneID; 9822255; -.
DR KEGG; crq:GCK72_024332; -.
DR CTD; 9822255; -.
DR eggNOG; KOG0977; Eukaryota.
DR HOGENOM; CLU_012560_7_0_1; -.
DR InParanoid; E3LEA0; -.
DR OMA; QGANASC; -.
DR OrthoDB; 72418at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR Proteomes; UP000483820; Chromosome x.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 2.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721:SF8; INTERMEDIATE FILAMENT PROTEIN IFA-4; 1.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PIRNR:PIRNR005546};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|PIRNR:PIRNR005546};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 72..425
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 458..574
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT COILED 69..244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 344..389
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 577 AA; 66763 MW; DA0CFC114AA1F101 CRC64;
MSESEYRSSI SVRPTFNRTL HSQSTATYGS TISSGTSRTL KITEIGGSTL TSGMSPFGNH
AASAIRESRT REKKEMSELN DRLASYIEKV RFLEAQNRKM EKDLDLLRGK WGHDSTSVKV
MFETELRTAK ELIADSDKER GQLEDQIRKL TEELNNYRNK MHEAERGADV TRKDLDNVLT
KLGALEAEIE LLKRRISLMD DTIGHLKREN HRMMDNLHHT RNAVEQETLN RIDYQNQVQT
LLEECDFIKR IHDSEIHDLL AMASRDTTVE NREYFKNELS SAIRDIRSEY DQVHNVHRTD
IESWYKLKVQ EIHTQASRNS LEQNYAREEV KRLRTTLGDM RGKMADLEGR NLLLEKQIED
LNYQMEEDMR SYEQSLNDKD TSINKLRDES KILMVELQML IDTKQTLDAE IVIYRKMLDG
EENRAGLRQL VEQVVKTTSI HQTKELESLR VLKGETTSHS SYSRSAKGNV VIQEVEPSGK
YIVLENISRR DETIGDWKLR RKIAGKREIV FTFPREFTLR AQKNVKIFAR GQGIHSPPDS
LVYDVEDSFG TGNDVVTSLY NKEGEERASH SQRASHN
//
