ID   E3LJ76_CAERE            Unreviewed;      1291 AA.
AC   E3LJ76;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=CRE-CAND-1 protein {ECO:0000313|EMBL:EFO95169.1};
GN   Name=Cre-cand-1 {ECO:0000313|EMBL:EFO95169.1};
GN   ORFNames=CRE_08654 {ECO:0000313|EMBL:EFO95169.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
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DR   EMBL; DS268409; EFO95169.1; -; Genomic_DNA.
DR   RefSeq; XP_003116273.1; XM_003116225.1.
DR   STRING; 31234.E3LJ76; -.
DR   EnsemblMetazoa; CRE08654.1; CRE08654.1; WBGene00056520.
DR   eggNOG; KOG1824; Eukaryota.
DR   HOGENOM; CLU_007157_0_0_1; -.
DR   InParanoid; E3LJ76; -.
DR   OMA; AYIPHFQ; -.
DR   OrthoDB; 68829at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:UniProt.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          553..797
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          338..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        340..365
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1291 AA;  144365 MW;  F64E2BD89F2B4E89 CRC64;
     MVILFVIYRS FFSRSYRLVF QMSGYIIGQL VDKMSNPDKD FRFMACNDLM KDLSLNTITL
     EDDSTAKVMR ALIRLLSDPS GEVQNLAIKC IGMLAQPSKI KSHHLEYLVE ELTPHVFSKI
     EQARDIHALT LKAMILNLAP TATNNATSTV IKRMLPKFID SLPSCAPDDA ARIDVLDLIG
     EVLLRFGDAV PEMHKSCLKV MVDHLYSSRS AIRKKAIIGI GHLASVINAQ LYDELVTELL
     TELAKASTSQ TSQTRTLVVA LSTIARASGS KFSKHTPQVL PHLIRFLSAN DESESENDDL
     REASLQGLEV FLYRSPQEVA AFEKDVIEQL TRALSYDPNY EYGDEDEDEQ MEDDEDDEDE
     DYSDDEDVTW KVRRAAAKAF EAMVSSHRES ILFLSQTIGP IIIGRFKERE ETVRTEILSI
     YIALLNQIAI LIPDLQKGIV STDENSIVTD DIVVIGDTKF STNYLSKSQL SLIQSLAEQK
     DLLLRSITKS MKKYPKTGPK CIELLSALIR AYPPVLENSL DEIIPGVAGI LTDKNATAQG
     KMIVLGFISK ALSLNEPAKF QRLLNPITTV MTRSISDNFY KVSAEGLAVS CKYIEVLKEL
     TSAGGNEEAK KLLDVIEKKF LANDTDQEVR EKAISSVSML LSSFKDQLKN ETPAILDKMT
     ERIGREMTCL GALRASSQMV VAGVVFSKEQ TKTILEKVVE YIKKTSRSLR MTCLNFVEKL
     MKHTPPSAIP EEELTQVLGE LPGLINDSDL QITNQSFSCL TYAFLNFPTC VSVHMKPILE
     AIIKLLQSCL IQGAALQSLL HLFTAIVKTD FPQKPTFESL LDSVTSPVYD NVPLSRQAQL
     AIASCAAVIT ESTQNIEKSR SLAKKIAQQL HVSQVSDSIR LFAMITLGEL GRRVPETYGD
     DFAVKPEELA IKAFNHLNED LKAAAAQTLG ALAVGNLNVY LPFILSQIRT EPKKQYLLLH
     ALKEVIVWES TVEESSKSTA LFRSAIGDIW GMLLSNAAGT EDGTRSVVSE CLGRLCSFDP
     DVLLPKLKEH MKSEDPAIRS AVVSSIKFMI NDEKRTVDIS LQKHIGEFLI AIRDEDLKVR
     RVALVVLNSA AHNKPALIRD LLPDFLPSIY EETRLRKELI KEVEMGPFKH LVDEGLDLRK
     CAFECMFTLL ESCVDKIDIT KFLTVMECGL SDQNHDIKLL NYLTLQRVAN LAPGQVLQRI
     DRICEPLKTQ LNVRPRGNAV KQEIEKLEEL KKAVIRVAYM LKTRLPDVER NPQYLDLYNT
     IKHNKELETL AEDVLKESQR AVVYDTPMDT A
//