ID E3LJK4_CAERE Unreviewed; 334 AA.
AC E3LJK4;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=CRE-NHR-238 protein {ECO:0000313|EMBL:EFO95227.1};
GN Name=Cre-nhr-238 {ECO:0000313|EMBL:EFO95227.1};
GN ORFNames=CRE_09148 {ECO:0000313|EMBL:EFO95227.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR EMBL; DS268409; EFO95227.1; -; Genomic_DNA.
DR RefSeq; XP_003116331.1; XM_003116283.1.
DR AlphaFoldDB; E3LJK4; -.
DR STRING; 31234.E3LJK4; -.
DR EnsemblMetazoa; CRE09148.1; CRE09148.1; WBGene00080913.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_1_1_1; -.
DR InParanoid; E3LJK4; -.
DR OMA; CNACAAF; -.
DR OrthoDB; 3020786at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06960; NR_DBD_HNF4A; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR049636; HNF4-like_DBD.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46011:SF3; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR PANTHER; PTHR46011; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-86-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 5..81
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 96..334
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 334 AA; 39178 MW; B839170C871AA6B1 CRC64;
MDGTKFACGV CDEKSDAFHF GALSCNACAA FFRRIVSSNQ SPKVQCSGNC DLTNHILRRM
CPSCRYDKCL KIGMKPSAVQ SKRAKPDEPP ERILEELKQS YEHLRELRRH TFKNETSKLT
FFEEMDEVCS IDINLILDTM MKKFTKLAPM TDDQHRCLIT NFLVLFILAD QCFRSIDSEY
TILANGNYVD VRNTDQHYQS TSGVVDEDRV AKTSMFLAPY WRLGRRMMFR RFTELKIDLN
EFMLFLGLIY WDFGLPDQTD ECIEVCLRMR TRIFEELRNY EHEKCRDDEF PLRIGEIMLM
LQMVPKYSTV MQEYKTIAIV YDLCAKHCPL FQIV
//
