ID E3LJP7_CAERE Unreviewed; 618 AA.
AC E3LJP7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=CRE-ACS-2 protein {ECO:0000313|EMBL:EFP00311.1};
GN Name=Cre-acs-2 {ECO:0000313|EMBL:EFP00311.1};
GN ORFNames=CRE_19083 {ECO:0000313|EMBL:EFP00311.1}, FL81_18962
GN {ECO:0000313|EMBL:POM40139.1}, FL82_17586
GN {ECO:0000313|EMBL:OZF80054.1}, GCK72_019611
GN {ECO:0000313|EMBL:KAF1753055.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFP00311.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|EMBL:EFP00311.1};
RG The Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:POM40139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM40139.1};
RX PubMed=26114425; DOI=10.1371/journal.pgen.1005323;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Reproductive Mode and the Evolution of Genome Size and Structure in
RT Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005323-e1005323(2015).
RN [4] {ECO:0000313|EMBL:POM40139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM40139.1};
RX PubMed=26394399; DOI=10.1371/journal.pgen.1005497;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Correction: Reproductive Mode and the Evolution of Genome Size and
RT Structure in Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005497-e1005497(2015).
RN [5] {ECO:0000313|EMBL:OZF80054.1, ECO:0000313|Proteomes:UP000216624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX439 {ECO:0000313|EMBL:OZF80054.1,
RC ECO:0000313|Proteomes:UP000216624};
RA de Groot N.N.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:POM40139.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PX356 {ECO:0000313|EMBL:POM40139.1};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:KAF1753055.1, ECO:0000313|Proteomes:UP000483820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX506 {ECO:0000313|EMBL:KAF1753055.1,
RC ECO:0000313|Proteomes:UP000483820};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KAF1753055.1};
RA Teterina A.A., Willis J.H., Phillips P.C.;
RT "Chromosome-level assembly of the Caenorhabditis remanei genome.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; DS268410; EFP00311.1; -; Genomic_DNA.
DR EMBL; WUAV01000005; KAF1753055.1; -; Genomic_DNA.
DR EMBL; NMWX01000394; OZF80054.1; -; Genomic_DNA.
DR EMBL; LFJK02000114; POM40139.1; -; Genomic_DNA.
DR RefSeq; XP_003115823.1; XM_003115775.1.
DR AlphaFoldDB; E3LJP7; -.
DR STRING; 31234.E3LJP7; -.
DR EnsemblMetazoa; CRE19083.1; CRE19083.1; WBGene00057740.
DR GeneID; 9838911; -.
DR KEGG; crq:GCK72_019611; -.
DR CTD; 9838911; -.
DR eggNOG; KOG1177; Eukaryota.
DR HOGENOM; CLU_000022_59_7_1; -.
DR OMA; CHVFIPK; -.
DR OrthoDB; 2596785at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR Proteomes; UP000216624; Unassembled WGS sequence.
DR Proteomes; UP000483820; Chromosome v.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblMetazoa.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:EnsemblMetazoa.
DR CDD; cd05917; FACL_like_2; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF24; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 67..459
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 510..589
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 15..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 69746 MW; 6D6A0BE2EBC89903 CRC64;
MRSITISRRL AHVLTSAHPA PSTSSIPSTD SHHLTHPSVH HQHKNSYIHG TSNIPLRNET
LGQTLRNTTE RVPDKEFCAF LKYPLRKTYE EFYHDVRQMA ASLYTLGLEK GDRVGVWGPN
YYEWVVLQYA CAFAGVIQVN VNPHYLHEEL RFVMRKTGMK VLFAPKRHKH SNYVHTLIEA
MPEMRRGKPG VGHIKSHDIP ELRHIVLFGD DVPVHGAWVY SDLMKAAGTD ERAKLEDMDR
KLRPDEPVNM QFTSGTTGHP KGATLTHFGL NNNAYFAGIR LGWDREDHRI CIPNPLYHCF
GCAVGVINAV NHGQTVIFPS KSYHVPDIFE AIQNERCTTM FGTPTMFIDV LKSPLMKQYD
TSSLRGGVIG GAPCPLALCE KMVKEMRMTD FAVIYGSTET SPLVTMSELH VDPFERIKSV
GSVMPHQEIA IVDEYGVPVP TGAKGELWSR GYSTMLGYWA DQDKTNLAIT RDRWYKSGDT
AVMNEDGTIN IVGRTRDMIV KGGENVYPTE VEQFLHKLDY VADAHVVGVP DDRYGENICA
WVRLRVEDEG KITPEKIIKD CKIGMAHYKV PKYVLIKKES EFPLTISGKV KKFEIQKISK
ELLGLGTVKS HFTEVVDN
//
