ID E3LL71_CAERE Unreviewed; 405 AA.
AC E3LL71;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=CRE-NHR-250 protein {ECO:0000313|EMBL:EFO99818.1};
GN Name=Cre-nhr-250 {ECO:0000313|EMBL:EFO99818.1};
GN ORFNames=CRE_19030 {ECO:0000313|EMBL:EFO99818.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR EMBL; DS268410; EFO99818.1; -; Genomic_DNA.
DR RefSeq; XP_003115331.1; XM_003115283.1.
DR AlphaFoldDB; E3LL71; -.
DR STRING; 31234.E3LL71; -.
DR EnsemblMetazoa; CRE19030.1; CRE19030.1; WBGene00082413.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_7_1_1; -.
DR InParanoid; E3LL71; -.
DR OMA; LMHFEEF; -.
DR OrthoDB; 2873905at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45680; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR PANTHER; PTHR45680:SF1; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 6..79
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 160..402
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 405 AA; 47005 MW; 3D0C7F936D2A0AA1 CRC64;
MELVQIQVCQ VCGAEGIHGN HFGAISCRAC AAFFRRAAFS KWSTSRCRSG NCTKSRFFCK
PCRVKRCFDI GMKTSNFQYN RDGLTSLVSS KKQFCTTVPN SNIPQTLECF VGRPEMVLFW
DADKPTHKSF IDVNSLVEEA LRIFSKPAES VYISNSCLHR LSIGMKEATK KNYEGFESIS
KINQKVVSET WQYYFLTVAK WLMHFEEFQK LDDEVKLKIL ESAWHIWATL DRHSATAAYR
RNNPNAPKSQ ILSRRGVLVD LKKVHFDSTW LSDYPAREIS YFLRQSSGEH FDIIGSLIDL
QPTDMEMTFM LAQLSFEYAG KRCQGEILKV TELFQHLLAN DLHNYYVNEL KMCKYSERLT
KLMKINNAIQ KNLWEHRPRM EVAKIFNIIK IEFSHPEMFK DSGFN
//
