ID E3LLB6_CAERE Unreviewed; 447 AA.
AC E3LLB6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=CRE-NHR-256 protein {ECO:0000313|EMBL:EFO99921.1};
GN Name=Cre-nhr-256 {ECO:0000313|EMBL:EFO99921.1};
GN ORFNames=CRE_19042 {ECO:0000313|EMBL:EFO99921.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR EMBL; DS268410; EFO99921.1; -; Genomic_DNA.
DR RefSeq; XP_003115434.1; XM_003115386.1.
DR AlphaFoldDB; E3LLB6; -.
DR STRING; 31234.E3LLB6; -.
DR EnsemblMetazoa; CRE19042.1; CRE19042.1; WBGene00082437.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_17_0_1; -.
DR InParanoid; E3LLB6; -.
DR OMA; MIRRQWK; -.
DR OrthoDB; 2879737at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06916; NR_DBD_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46397:SF5; NR LBD DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46397; NUCLEAR HORMONE RECEPTOR FAMILY-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 3..79
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 170..447
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 79..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 51608 MW; 9D1C44E3408050BB CRC64;
MSRGNCKVCD SPNATNFHFG AHACKACAAF FRRTVKTGQI YTCAGDNSCE INHALRQNCR
QCRLAKCQEA GMKEDLVQGQ KVGISENGTM KRSSPMEEQP STSSYYDHPT PPGPSESQWD
NHYHQPPIKS MRHEQEDLME LEEFQQFIQI PTHTSSSMLI LPVTPVDNLE EEERLYGLAS
LYMEQLVNLN MRRRLTYAKV TLAAMFDGPC VCVSEKSNPF EISDLRPFDH RSYRYKNRND
YTMILDYVNR FPEFHLLNKS EKTVIFQTTA AVDALADPAY YSQVMYPNDS VFVTREGKFI
RMDPLPSTEL DLDSGVYSSE DISMYKSMVL MIRRQWKNVN LPLKKLKMSL SEFSLFKALT
IWHYNYYKLQ DTGRQISARQ RDDIFRTLLL ICKDEGHDDP VLRVSEIVLA VGIVMTEVHE
LVTSLFEIIV FDDVDDPILK DMLKFQY
//
