ID E3LPC5_CAERE Unreviewed; 1213 AA.
AC E3LPC5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=CRE-EEA-1 protein {ECO:0000313|EMBL:EFP05522.1};
GN Name=Cre-eea-1 {ECO:0000313|EMBL:EFP05522.1};
GN ORFNames=CRE_27564 {ECO:0000313|EMBL:EFP05522.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS268412; EFP05522.1; -; Genomic_DNA.
DR RefSeq; XP_003114184.1; XM_003114136.1.
DR AlphaFoldDB; E3LPC5; -.
DR STRING; 31234.E3LPC5; -.
DR EnsemblMetazoa; CRE27564.1; CRE27564.1; WBGene00052809.
DR eggNOG; ENOG502QWB5; Eukaryota.
DR HOGENOM; CLU_256550_0_0_1; -.
DR InParanoid; E3LPC5; -.
DR OMA; EAHWKTK; -.
DR OrthoDB; 2881467at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:EnsemblMetazoa.
DR GO; GO:0030139; C:endocytic vesicle; IEA:EnsemblMetazoa.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:EnsemblMetazoa.
DR GO; GO:0006897; P:endocytosis; IEA:EnsemblMetazoa.
DR CDD; cd15730; FYVE_EEA1; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.390; L1 transposable element, trimerization domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR PANTHER; PTHR23164:SF30; LD23155P; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF69979; Eea1 homodimerisation domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 1154..1212
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 104..138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..240
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 282..341
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 790..832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1213 AA; 140767 MW; C27FDE302DB385F8 CRC64;
MLQRFKKQVS QVANELDGRL SNSSRASVSS QDSQSQPQQK SENEQEIEGF LCPICMIEHG
SADELTAHFE NKHADFKTSA NRNHPEYAPP QAAPLAFGTK DQEIEELRIR VTEEKRFAER
IKEELDNIKT VMANASDVTE DEIPYMAQQI QVLTADKGMV TRQFLELEKE SGQQTRELQQ
VKQERGDLMA KLKQLSVNLR ELTDENETTK VEREDLKREL KVANSDVVRY EIEVARLEKM
LDQRPSEDDV NVLRTELVNS QTIMDSISQE KDIEIKEHLN SIRNLSMERE KQHAINENLE
KKILEGEETV KQLQISYDSQ SDELKQRNER ILQLEERIQE NVFELAENHQ LVKRLQDKVK
EAESGVQLFS GINNSNEEMI NSLKAKFEKN SAEQKRMQTV FDEKVAAQGE RLKSMELSNL
DLTNEMSSIS TLLDKERTLV EEKNAEISER DSSINELREK LAESEKKATK YSNDLKEQTT
LVENLTLQLN KVQENSKELM EKISTGEGGA KMAIEQMEQE KEKLTKELQE LAEKNKKASE
EFEHKISELE KKLREAEASR TDKEQKWKQE KETFERKIAE AEDEIRRKSE RFVEMEKEME
EDRQKASDRT LKLKDALVKS EKDLETVKKE SEERDKVVRE KDAHLEENKK RIEDAVQKLE
EAEKRARELE ASVSNRDSAV STKDSELAEM KSKLTESNSF IEELKVQVEK VSSELAEKQQ
EVESLMTEMH EKEAHWKTKR DEFEAQIVRN QEENEEASTT LKSLQDQLTK EKEALSEEKS
QLSSFKSQLE ESKNENERLL RSDEEKAEEI NKLKLSLSNS NHEREELIAT TESIRSENEN
LTSKLQALED SRKQAEEKNS ANVESLIAEK SRLEKEVEER ESTIQSIQEA IESKDNEIES
LKSTSRIVED ELLSKISLIE SFNSRIEEFE KEMASGKRKI EQLEAEKAEE MEKLVIVSRT
QSQKQEEVEQ LQKEMAEKSK TIERVCSEFI MTSSKTQFEA MFTDVQQTLQ KEVNEKNQEI
EKLLERIDSL ESSTQQKVED LESRLTQRER LVESLEAEMA AVRNAEQEKL DEQKKLKEEY
DELKKAEAMW QAEKDMLIER CLGNESDIEY EKERAQENKR RFDEALSAMH ELGRANQSLQ
IDADRYTSRK WLDDAEAINC TECGKVFSLT VRKHHCRVCG KIYCNPCSSK SVRIASAKHP
VRACNHCFAE SQK
//
