ID E3LPP8_CAERE Unreviewed; 440 AA.
AC E3LPP8;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=CRE-CEH-32 protein {ECO:0000313|EMBL:EFP05375.1};
GN Name=Cre-ceh-32 {ECO:0000313|EMBL:EFP05375.1};
GN ORFNames=CRE_27322 {ECO:0000313|EMBL:EFP05375.1}, FL81_14736
GN {ECO:0000313|EMBL:POM34495.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFP05375.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|EMBL:EFP05375.1};
RG The Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:POM34495.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM34495.1};
RX PubMed=26114425; DOI=10.1371/journal.pgen.1005323;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Reproductive Mode and the Evolution of Genome Size and Structure in
RT Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005323-e1005323(2015).
RN [4] {ECO:0000313|EMBL:POM34495.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM34495.1};
RX PubMed=26394399; DOI=10.1371/journal.pgen.1005497;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Correction: Reproductive Mode and the Evolution of Genome Size and
RT Structure in Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005497-e1005497(2015).
RN [5] {ECO:0000313|EMBL:POM34495.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PX356 {ECO:0000313|EMBL:POM34495.1};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; DS268412; EFP05375.1; -; Genomic_DNA.
DR EMBL; LFJK02001048; POM34495.1; -; Genomic_DNA.
DR RefSeq; XP_003114037.1; XM_003113989.1.
DR AlphaFoldDB; E3LPP8; -.
DR STRING; 31234.E3LPP8; -.
DR EnsemblMetazoa; CRE27322.1; CRE27322.1; WBGene00052337.
DR GeneID; 9811330; -.
DR KEGG; crq:GCK72_018090; -.
DR CTD; 9811330; -.
DR eggNOG; KOG0775; Eukaryota.
DR HOGENOM; CLU_049495_0_0_1; -.
DR OMA; EMWHEAH; -.
DR OrthoDB; 602349at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0009886; P:post-embryonic animal morphogenesis; IEA:EnsemblMetazoa.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR PANTHER; PTHR10390:SF33; PROTEIN OPTIX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 182..242
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 184..243
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 262..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 49724 MW; 23B961C33F13973B CRC64;
MFTPEQFQKM VNQLSNFSQL GQMFQPGNMA MLQALQANGA APTPSLFPTM PVMSPLAAPS
SPTTSNLTAD QIVKTCEQLE TDGDVDGLFR FICTIPPQKA QEVAAQESFL RARALVCFHA
GHFRELYSIL ENNAFSKKHH PKLQEMWHEA HYRDQEKSRQ KSLCAVDKYR IRKKFPMPLT
IWDGEQKTHC FKERTRSTLR EWYLKDPYPN PPKKKELAQA TGLTQMQVGN WFKNRRQRDR
AAAAKNKMNT TGVELRKIAS DMSDSDDDFE GSMTDSPSPI DEPKDLSKSH IPKLQASLLP
KMNTPFDMFA AAAANPFMLN PAIYMSFHNF FNQINKNSQA EEEENTDVKA IADAEDEVET
TTKKRSKLSI DEILNIKSEV SPSQCSPCSN ESLSPTHKVK KEVKKEDDEA VAEDDFDIMK
TRELDDSAHA SPKSSTSQSE
//
