ID E3LPY9_CAERE Unreviewed; 791 AA.
AC E3LPY9;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=CRE-NHR-207 protein {ECO:0000313|EMBL:EFP05437.1};
GN Name=Cre-nhr-207 {ECO:0000313|EMBL:EFP05437.1};
GN ORFNames=CRE_27048 {ECO:0000313|EMBL:EFP05437.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR EMBL; DS268412; EFP05437.1; -; Genomic_DNA.
DR RefSeq; XP_003114099.1; XM_003114051.1.
DR AlphaFoldDB; E3LPY9; -.
DR STRING; 31234.E3LPY9; -.
DR EnsemblMetazoa; CRE27048.1; CRE27048.1; WBGene00052425.
DR eggNOG; ENOG502RZKC; Eukaryota.
DR HOGENOM; CLU_349386_0_0_1; -.
DR InParanoid; E3LPY9; -.
DR OMA; CNPAVCS; -.
DR OrthoDB; 2875926at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06960; NR_DBD_HNF4A; 2.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 2.
DR InterPro; IPR049636; HNF4-like_DBD.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24083:SF75; NUCLEAR HORMONE RECEPTOR FAMILY-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 2.
DR Pfam; PF00105; zf-C4; 2.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 2.
DR SMART; SM00399; ZnF_C4; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 2.
DR PROSITE; PS51843; NR_LBD; 2.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 2.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 35..112
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 174..403
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT DOMAIN 418..497
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 560..791
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 791 AA; 90544 MW; 6E159799E3FB1C1C CRC64;
MLEVNNYALK ADGPKSEDVT TPKRDLSKNA RNILPEYCEV CGNRAIGYHY DVATCNGCKA
FFRRTIITGR KFLCKKGHKC LEKADPKARR LCPGCRFEKC EKVGMNPMNI QAEMTQKGEL
LRQQFIASRE FEQSINRTPT PIEDKLSIAI SKLTLIEDQL DDLFNSNIPA HYGDMRTLTE
ILQMNPILEV SRIPDLKFLT SQLFPAHAGF CHNIYLSMVE FTKMFDSFSK LSTDSIKKLI
RHGASMCVGL MASRRSVRKF NADSLRRTDG TIAGKPDRSW NGIWVEHKKM IQKVLHSFVR
NKIDDVEFMF LKAIAICNPA VPDLRKADQV VVEKERFRYA TALLDYCFRT YGSTHGADRF
GSILSVMTIM ENQQREEKCF YVILRSYFSH VDMLLDDEKP CSSRSKILHL EKDKNVLPAK
CQICRNPAVG YHYDVASCNG CKAFFRRTVI TGKIIKCKYG KRCLEGDDPT DLKKRLCGDC
RFTKCEEMSM NPMSIRAEIT STEGKKLKNE LVKKRKLAEV GISKKIKFED EMTVVLTRLT
IMESQLVDLF NSNLPKHYVD LRPLSDILVD KPTLEASKIP HLSFFGNELF PDHGGMAHTS
LLAVVEFIKM MDFYQQLDSD SLLKIVKHGT LMVRGLMNAE RSIRRFQSDC IRRADGSVAG
KPMRNYNGVW VEQRKIVQKI LYAFLRNNID STEYLFVKAI VLCNPAVIGI SMEAQKVVEE
ERQKYARSLF TYCLRQHGSR FGPDRFAALL SIMSVMENQQ KEEKSFNVIL RSFYSNVTVL
VSPLYDEIMG S
//
