ID   E3LTC1_CAERE            Unreviewed;       263 AA.
AC   E3LTC1;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=protein-histidine N-methyltransferase {ECO:0000256|ARBA:ARBA00012533};
DE            EC=2.1.1.85 {ECO:0000256|ARBA:ARBA00012533};
GN   ORFNames=CRE_25466 {ECO:0000313|EMBL:EFP09125.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. METTL18
CC       family. {ECO:0000256|ARBA:ARBA00038126}.
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DR   EMBL; DS268414; EFP09125.1; -; Genomic_DNA.
DR   RefSeq; XP_003112871.1; XM_003112823.1.
DR   AlphaFoldDB; E3LTC1; -.
DR   STRING; 31234.E3LTC1; -.
DR   EnsemblMetazoa; CRE25466.1; CRE25466.1; WBGene00054862.
DR   GeneID; 9825240; -.
DR   KEGG; crq:GCK72_009678; -.
DR   CTD; 9825240; -.
DR   eggNOG; KOG2920; Eukaryota.
DR   HOGENOM; CLU_038704_0_0_1; -.
DR   InParanoid; E3LTC1; -.
DR   OMA; AKSHYFG; -.
DR   OrthoDB; 276605at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR019410; Methyltransf_16.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR   PANTHER; PTHR14614:SF39; HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG; 1.
DR   Pfam; PF10294; Methyltransf_16; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..263
FT                   /note="protein-histidine N-methyltransferase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003175611"
SQ   SEQUENCE   263 AA;  29854 MW;  D1979D6742D8E9D2 CRC64;
     MYFLPNLWIF AFQLLLIPEK DVHNRTFKSE TSKMNVLKLT SGREISYLNE VEIRMGIDER
     NGEERYKNEL ENMGISDITV HKYEGGFKIW ECTIDLCDFI EENKTKFEGK SVLELGCGAA
     LPSILTAMHG AKEVYAQDFN ASVIEFFTVP NFEENPHSAI VQGEAMGWED VPTKLNGRKF
     DFILSSETIY NEDDYQNLHD AVAATIKDDG VAWFAAKFFY FGVGGSVPSF CQFINERGVL
     IASETKVITA SVPRRIIEIR KAL
//