ID E3LUT7_CAERE Unreviewed; 744 AA.
AC E3LUT7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=CRE-CPT-6 protein {ECO:0000313|EMBL:EFP11092.1};
GN Name=Cre-cpt-6 {ECO:0000313|EMBL:EFP11092.1};
GN ORFNames=CRE_31132 {ECO:0000313|EMBL:EFP11092.1}, FL81_18859
GN {ECO:0000313|EMBL:POM28159.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFP11092.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|EMBL:EFP11092.1};
RG The Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:POM28159.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM28159.1};
RX PubMed=26114425; DOI=10.1371/journal.pgen.1005323;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Reproductive Mode and the Evolution of Genome Size and Structure in
RT Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005323-e1005323(2015).
RN [4] {ECO:0000313|EMBL:POM28159.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX356 {ECO:0000313|EMBL:POM28159.1};
RX PubMed=26394399; DOI=10.1371/journal.pgen.1005497;
RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M.,
RA Ahearne T.E., Cutter A.D., Phillips P.C.;
RT "Correction: Reproductive Mode and the Evolution of Genome Size and
RT Structure in Caenorhabditis Nematodes.";
RL PLoS Genet. 11:e1005497-e1005497(2015).
RN [5] {ECO:0000313|EMBL:POM28159.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PX356 {ECO:0000313|EMBL:POM28159.1};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR EMBL; DS268415; EFP11092.1; -; Genomic_DNA.
DR EMBL; LFJK02001570; POM28159.1; -; Genomic_DNA.
DR RefSeq; XP_003112571.1; XM_003112523.1.
DR AlphaFoldDB; E3LUT7; -.
DR STRING; 31234.E3LUT7; -.
DR EnsemblMetazoa; CRE31132.1; CRE31132.1; WBGene00052163.
DR GeneID; 9824610; -.
DR KEGG; crq:GCK72_017932; -.
DR CTD; 9824610; -.
DR eggNOG; KOG3716; Eukaryota.
DR HOGENOM; CLU_013513_2_0_1; -.
DR OMA; WKLSTSH; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF99; CARN_ACYLTRANSF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 149..733
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 445
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 744 AA; 84845 MW; DCBA4ABE3D6017FE CRC64;
MSSKKTVRPP YPLPTKFPTP LEQASYKTYN WFENRLWPVK PLPFVATTVA LAATLHYKYP
ENAILDVLPK FSSEAAEIAK TALVSAIGTY AGVFTLRKLL KYFYFSYKGF LFDNPKKPSL
KTKIWGIVRH ILSISPPILE SCDTLLPNLP VPALKDTISE YLDSMRHILS DQELETITKQ
AQDFLENEGK TLQRYTNLYS LFTDNYVTSF WQKYAYLHGR YPLLINSSVA HCDLLKDKEA
TRAHRAARVT WIEVMSHLAV NRQQYKPLGD GLVCTRHYKN MYAVTRVPGE EIDQLKLHGV
QKHIVVVLRG KYYKIHVVDD KNNIYNIEQL TKIFHEMISR DEKEDGVIGK VAALTHDSRD
SWCKNRKKYF LENETNFKIL QEIESAVFFL TLDEDDDYGY DPERPEVLNN FLSNTLSGDG
ANRWVDKSLN YICSKNARCG GTTEHSIADG AEFDHIMENF VYVDLEILKY QSVEEQEKMA
IIKNDEGKTL KLATPLNFEV PDEEMLTEIT RCYEAHQVSK NDLDLFALAF RDFGKGRIKK
CGVSPDAFIQ MAIQLANYRD QGKFVLTYEP ASARFFANSR TETLRTVNDH SCAFVEAMLN
ENESKDAKIA LLKKACENHV LRNKKCMVGQ GVDRHLFVLY ILSQGTGTPS PFLDNYISQK
WKLSTSHVPN VTNQCDEDTD PNNTWLGACF GAVAADGYGI CYRFGGNHGI FANITSYRSA
ANTDSTRFAK LLAESFHELS NLFV
//
