ID   E3LW25_CAERE            Unreviewed;       898 AA.
AC   E3LW25;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=CRE-DUO-3 protein {ECO:0000313|EMBL:EFP12534.1};
GN   Name=Cre-duo-3 {ECO:0000313|EMBL:EFP12534.1};
GN   ORFNames=CRE_29618 {ECO:0000313|EMBL:EFP12534.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268416; EFP12534.1; -; Genomic_DNA.
DR   RefSeq; XP_003112100.1; XM_003112052.1.
DR   AlphaFoldDB; E3LW25; -.
DR   STRING; 31234.E3LW25; -.
DR   EnsemblMetazoa; CRE29618.1; CRE29618.1; WBGene00059866.
DR   GeneID; 9810130; -.
DR   KEGG; crq:GCK72_002376; -.
DR   CTD; 9810130; -.
DR   eggNOG; KOG1864; Eukaryota.
DR   HOGENOM; CLU_013168_0_0_1; -.
DR   InParanoid; E3LW25; -.
DR   OMA; AAICHIG; -.
DR   OrthoDB; 2883957at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   CDD; cd22755; OTU_CeDUB-like; 1.
DR   Gene3D; 3.90.70.80; -; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR   InterPro; IPR003323; OTU_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR24006:SF888; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 2.
DR   PROSITE; PS50802; OTU; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT   DOMAIN          260..898
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   DOMAIN          640..763
FT                   /note="OTU"
FT                   /evidence="ECO:0000259|PROSITE:PS50802"
FT   REGION          117..240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          761..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        761..796
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        797..817
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   898 AA;  101017 MW;  3E87933AD3FD4DF5 CRC64;
     MTDKFVVDVT IFANTSEKML ITLKDHRIKF EGRTIKVLKA SSFETVREFD SSLLLNKPLK
     HPDVRERTVL SIQFASSPGL KLAFHNSNRD YAQYVVEEYN KFLEANKDKV QQVRAKTTHV
     PTVGPQRSIT SSVPTKENQY QEYAPKIPVM KPSVSANSYS PSPKRKPLLP PVSSISPRNF
     NVAPGSAQKP STSSGNPNIY KREPNTSSTK SPGQHARVSQ LRSNEKLATQ NGSRNGLQNS
     ADAHREKLNM LMPETIPRKK GLKNTGNSCF FNATMQAFAS SPSIVSRCNQ LSRVTSMYSR
     VFNVEDDSIM KFKLNVFEGF LTMIQHLTRT PDIVSIQKLK EIRRSAGFLV GRFHTPEQQD
     VHEYLLLVID CINDVIKDKV KSPPDVKSNE SPVFVKALAG LNPMHAIQSI TEKEYQCVNC
     SKKSVESVSN LIVQLAIDET RNGSIELGDL LDVYFATESL DKRCSSCNTE DAFVRERFVK
     FSPCIILNPL RTQHSGGEDG SRKDSRQINV PLKLDLTKFT SFAKVCKSDE NLNLNGVGTP
     QISSSKITST KNLMLNGGMK CSSPFKVLGG AKEPSEDDDI QFDNEIINNP FYFELISCPE
     ELKKMARLLG IKYNKKFMEY HVSILKEKPS TDMKKNDYPD EKSVIDGDGN CFFRAISWFL
     TGTEGHHKQV RKVLVEYMKN NQSALEKHCT APSYERHVRD MSKDATWATG CEIAAISKLL
     NVNIYTFLPS GWSLQQPQTG VASKKGSIYL NNLSEHYEPV TSLKKHGADS RDRRAHKRRC
     VRDGGEEGDA EISKNAESSS KNKTITPAKL PTKQKPTRSC NTEKKPKEAD PSELCIYQLI
     AAICHIGNMK FGHYYAYTKN LNDDKWLKCD DHKITDVSVG EVIDAVSYRC HLLFYERQ
//