ID E3LWB3_CAERE Unreviewed; 1508 AA.
AC E3LWB3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CRE_02863 {ECO:0000313|EMBL:EFO83478.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS268417; EFO83478.1; -; Genomic_DNA.
DR RefSeq; XP_003111617.1; XM_003111569.1.
DR STRING; 31234.E3LWB3; -.
DR EnsemblMetazoa; CRE02863.1; CRE02863.1; WBGene00055281.
DR eggNOG; ENOG502QQEE; Eukaryota.
DR HOGENOM; CLU_003777_0_0_1; -.
DR InParanoid; E3LWB3; -.
DR OMA; TANSWIN; -.
DR OrthoDB; 2891005at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR003125; WSN.
DR PANTHER; PTHR32525; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR32525:SF3; PROTEIN-TYROSINE-PHOSPHATASE-RELATED; 1.
DR Pfam; PF02206; WSN; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SMART; SM00453; WSN; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 1073..1318
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1239..1309
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1395..1508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1358..1385
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..20
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1004
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1395..1414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1455..1477
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1478..1508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1508 AA; 168455 MW; 18A1015CB3E2A007 CRC64;
MGAKIKSKNS RKKRSKNLAQ TKNKSKSFMK ILTILILIVT TSNTVSGNDS PNLHLQKRGP
RASQGNFQPI LENMERLARI SNGVSLEIGL HDESTPADEV ISELLHMGSL KPDAIISMDS
SAVNGAITGI EDVNKQLESD VDVKAIETRL INFEKVRLRS KFMLNMTEFS EKDEYKAVLD
NVTAINWSIS GNISTISGTA GALQRYYLKI DEWSNGMSED TSKKVVAQLP TIGIQLEEAE
NSMQTLFNDI IPLVAAAKQL KPRSIFLDIL NEEKKIRAQL KGKIIHQNYK KSVMNNLKTI
QTFRGSLESS KPVFESLQKL AQNRFKKQSF EYTSGFLKGS VDLNNLGADI SNDWIVKRID
ESSIVTTSLN KAFSYFEDLK NAIVNVEKSW KPLADESKRK SVQMLVDALL SVISESEDSG
KVETVVDQLA SCGKSLTQET PDSSKLDIVS GKIRTFNDVV DKLSLFEYAQ VLGDLSAFKN
LQERAENKTD TVEDFVKKFK EMPTFGSAWN ALQKLETDLK YLSKTTEEIP GKLAEISSEF
VNIDNYHTEI SMPTYIQFFT CLHNVTESSL VKDSVETLQK VRLAYDEANN ARPVIAAIIG
SKSNMETART SAGNMKEVMD REVTALKESF PDAQRASKNL GNGVRGLAAI NSIHNSWPDL
DALFKNISGI VEAGKSVGLS QQHQTALQKL ALLRNSLTDT HKGIEVFLHT VGTIQNLRKK
RNTKITDIKT SASVMEAASK IKQLPPGVSD DVSSIKEALD LLNVATSSKY AKEVEVMGLL
DRLNLDFSGF QPAATSLGHV DNFFATYGAT MASASVTIPS PIPTPAPSQP PNQSPVVTTI
ASMMMQIVTS TVIPTTEAIS IGMIAKYIGL TLLVIGGIGG FGALVYCCCI KPKDAPPPDD
LNNEEEERKR KQKEETAKKE KEEKEKPPKQ KEEPEKKINK DQERNNENAN KNNDVSAPGA
SDSSDSLPTA RENTLRATPA PSNDRLPSEV DAVEPSKKDS KVEPEVVAPA VVKTEEVKPK
RPILVENLYS MVISQVTRFE DYAHLLFSPQ HYFKNKIDIM DKTGALEVKG VVEKRQETRK
QQFLCLPETA VKLRDKAFIH ANTIVIGLRK CILAQSPLDG NEKLLFVKKK EPTMEKHLDM
IVQKKVPLTI MLGDFVEFGH NACGRYFSVR KDESIQIGKH EVTTDNVSDN VSGFTDNKDY
KLYNITVRSE NKNGKRIEHK LDILQFVGWE ESGVPDSVEH CFEMIRFAEN YAGTILIHCS
NGVSRCGVLI AIKYGMEMIK SKVFKDVFEL IQDIRRFRYG AVKEYAQFMF VLLSLAVYMI
RELGLKTIPS YDMLLYFNQN LKRYESYENN KWKKCGDESA KKRVKKELKE EFDAAREKAL
EREKEVGNEG TVFENKLIEE KRQEEEEEAR RKKPKRSASK TTVTEGAMEK TSDERPSAEA
AMGLVPEAKE KSKKSKKSLK SNKPSKKASK KGSKNSVKSR KTKESKKDRK SKETSKKTNN
SNNAKKET
//
