ID   E3M0T7_CAERE            Unreviewed;      1161 AA.
AC   E3M0T7;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Domain of unknown function WSN domain-containing protein {ECO:0000259|SMART:SM00453};
GN   ORFNames=CRE_06666 {ECO:0000313|EMBL:EFO88815.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268421; EFO88815.1; -; Genomic_DNA.
DR   RefSeq; XP_003110026.1; XM_003109978.1.
DR   AlphaFoldDB; E3M0T7; -.
DR   STRING; 31234.E3M0T7; -.
DR   EnsemblMetazoa; CRE06666.1; CRE06666.1; WBGene00079304.
DR   eggNOG; KOG4177; Eukaryota.
DR   HOGENOM; CLU_002600_0_0_1; -.
DR   InParanoid; E3M0T7; -.
DR   OrthoDB; 1327985at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR003125; WSN.
DR   PANTHER; PTHR22956; ANKYRIN REPEAT-CONTAINING PROTEIN F37A4.4-RELATED-RELATED; 1.
DR   PANTHER; PTHR22956:SF14; BRCT DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF02206; WSN; 1.
DR   SMART; SM00248; ANK; 2.
DR   SMART; SM00453; WSN; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..1161
FT                   /note="Domain of unknown function WSN domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003174918"
FT   TRANSMEM        816..840
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          27..95
FT                   /note="Domain of unknown function WSN"
FT                   /evidence="ECO:0000259|SMART:SM00453"
FT   REPEAT          924..956
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   COILED          694..721
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1161 AA;  133434 MW;  782472D99AFFF00B CRC64;
     MLIFFFFISF SLLFSLTHQN VPPPEPTDLE LVTEDFLTLA RITNAIFLQA SLIRKNLDTR
     ETIAELLKID QTDLLGILNI DTQSALSKVE ELKKKSSNIW KARMTPDSNF GEIISDLKRV
     WYVLKYIRVS PLIANISTDE LNAAVISVAE NISEFSNACK IAELRSLRSR TYKYSEQSLD
     VDEDDASEDL RKFGKYLKCF KKCFDFVNSF SKSLQDASFW DIYKMYELTY KASRMFFETN
     SLNKYIPKLI NDLAITKELR EYWKNSGNSG SEILKSLGSY EDHDSKLEPT PPVLTVAFRT
     PEEMLQINKD LENPWFQKHF IRGSKAIDNL KKSLEPLRPI SESVQNLSKL WESFDVLMKS
     GPAKLRVKKV ASILTTLELM VKNQSLLTHD DFLATSSKIL IDCTIKPDDG FTRLQKNFEK
     HEKPLKKVRE ELRNLQDRFD LFGKTINTRK ANFDIIDSCL NALEITVQSS RKGSTKKMTA
     LQNAIRSFSN CTASRQMTLK LIDLIAIFRE YLDSFNNFET AYTKFQIEMN RRETLSNSGE
     IVQFSEVLEK SKVNETLNCL MLKNFEPEKL MQSITFARTF SDFPNQEKLD TAKTFLETLQ
     NIQASLKTVE NNFNLTGNRT KRAAVPSNPV LTLNNSRFHS EDMGICAIAL SNMVDVQAKR
     GDLLKIKKFT GRVGEKIDSG GVVLKNFKNP EASIRTLLEQ VDEVNEMAKK LRNKVPSKEA
     EIFNTVAGID GIIGNREILW KMWKENKGKQ EFINAEKKIN TLISLNLDFQ TYQSRLLDGR
     FTVITLKKYF DEIFGHVKKS NPNEKTKVVV EKHTPIVLII LIVVGVLLLL IIGVIVIYGL
     SKKGREKYKN LYLFYFGKPD EFEKRWRYSV RGLQDGAHLS SDLQSFMDKV NGENALLSSI
     HEINKTNMLI ALKRGVYINA YNKFGNTALH SATKGGHPEL VDALIRHGAD RTLLNVENRT
     PEQMIPFKFQ ILYPERAERY EQIQNIYKKY QKKKYKIRVP EVFPLTSYRI WIEDRTDDKL
     TNQFMDVFQS IHQGVLYDTV LQWSEAMAKG DVPYLYGVQV AIAMKACSNI VTLSALITNH
     GGILLDQFPD KSNYNSGSHP YMHSHLGPLF VLHDGETDLS KFKNDKMFTL FTEDEFIAFM
     LRRDIKKDSS ENPICVLREQ E
//