ID   E3M226_CAERE            Unreviewed;      1155 AA.
AC   E3M226;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Kazal-like domain-containing protein {ECO:0000259|PROSITE:PS51465};
GN   ORFNames=CRE_07311 {ECO:0000313|EMBL:EFO89856.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268422; EFO89856.1; -; Genomic_DNA.
DR   RefSeq; XP_003109714.1; XM_003109666.1.
DR   AlphaFoldDB; E3M226; -.
DR   STRING; 31234.E3M226; -.
DR   EnsemblMetazoa; CRE07311.1; CRE07311.1; WBGene00058276.
DR   eggNOG; KOG3649; Eukaryota.
DR   HOGENOM; CLU_275975_0_0_1; -.
DR   InParanoid; E3M226; -.
DR   OMA; FKFFACK; -.
DR   OrthoDB; 2878621at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   CDD; cd00104; KAZAL_FS; 5.
DR   Gene3D; 3.30.60.30; -; 13.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   PANTHER; PTHR10913:SF45; AGRIN; 1.
DR   PANTHER; PTHR10913; FOLLISTATIN-RELATED; 1.
DR   Pfam; PF00050; Kazal_1; 2.
DR   Pfam; PF07648; Kazal_2; 13.
DR   SMART; SM00280; KAZAL; 15.
DR   SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 13.
DR   PROSITE; PS00282; KAZAL_1; 1.
DR   PROSITE; PS51465; KAZAL_2; 10.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT   DOMAIN          1..51
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          102..164
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          229..286
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          507..561
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          562..612
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          662..721
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          743..794
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          848..903
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          904..954
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   DOMAIN          1047..1104
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   REGION          426..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1155 AA;  129602 MW;  41BC4B43695161AF CRC64;
     MAMPPLPPNC DCPSVIRPVC GTDNITYNNL CVLRCVQRTN QDLLFFYNDT CCEQKECENG
     GTPLCDNFGK THANKCHFSL FQCIMERSMG LFAVKLHDGP CSAKDCNHNC THTEFDPVCD
     SNGSVYRNLC VFEMRRCELQ LESQRIQLAE DRKFCLKNRG SQRFKLAGVE SYSSYAEEPY
     EQSTETTTST TTVITTSMKP EEGFLNKVIA KTNAQKPSYQ NNQSPLTRND LNRVCSITEC
     DKAWDPVCDT RNRTHKNVCQ FKFFACKINK IDGSIIDIAH TGACKARKST CIICPKDEKR
     IPICDNQNMT HSDLCSFIQY NCEARNNDDE ERVLVHIKSC HARSPQFTLK DEMCPRTCSR
     DVKPVCDEAN NTHQNLCHFQ QYNCNMRKLG IRSPYLRYLR PCVKNRKIDT AVENVEMRAS
     VSNIEIQTNK SRESTPASPT ISKPESSEKT TFIVSAFEKV MKSTTSTERP TTTITSITTL
     STTPLSTEPA ITFTSTEPFT ETTTLPDVAF FDCPKPNCPT DGQPVCDSAG NLHGNLCEFT
     YYRCIAASKG HQIHIATEEN CISKEACEMP CTEDKHPICA SDFSTYENLC QFRKQKCLDS
     ELEVLFKGKC NECLDSPCAL PAENSPDESF VCLEDQSTKS LCEYQMLSCI FERGYGVNLT
     VQYIGTCCPP VESCDNEKPD PVCTDSGATF LTECELNIEN CKLKKQDQPK LVVVSKGVCE
     KDMLTDDFSS NRNFQKPNIE FKRENSFNCS MECDNSYDPL CGTNGVTYTN ACSLQKEICD
     TANSTIEVAY TGMCCDTNSK AALIRLENKL KTSKMHVVQN ICHFGIKRCI AERTFGDVLT
     IEKFEVCNQI AACNAQCPKE YSPVCASNQQ NIVNECELNK IRCLVENNVT TGEKLVKEYD
     GECCRLENCD FSTFSPVCDT EGVTHANMCL MNHNACIQIK KFKKTIQVSY QGQCCNQPCD
     EDDAPVCDGD TTHPNTCKFR IAQCEAERVN KTISIAYSGD CCILPKGECE TSGAVCDSEG
     QTHSNHCVYQ QKRCIAERIS KKTLNIVHTG ECCALASCPK TGQPVCDSRG RTHDSLCHFH
     NSKCIFDKIH TQNTTLTLDY QGKCCPAGCT DELSVICDQH ENIYRNSCYF NLKACETWRR
     TQDVLLATPC PLLRT
//