ID E3M246_CAERE Unreviewed; 2426 AA.
AC E3M246;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=CRE-SMA-9 protein {ECO:0000313|EMBL:EFO89915.1};
GN Name=Cre-sma-9 {ECO:0000313|EMBL:EFO89915.1};
GN ORFNames=CRE_07245 {ECO:0000313|EMBL:EFO89915.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS268422; EFO89915.1; -; Genomic_DNA.
DR RefSeq; XP_003109773.1; XM_003109725.1.
DR STRING; 31234.E3M246; -.
DR EnsemblMetazoa; CRE07245.1; CRE07245.1; WBGene00058412.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_001604_0_0_1; -.
DR InParanoid; E3M246; -.
DR OMA; WDISTKI; -.
DR OrthoDB; 2883491at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:EnsemblMetazoa.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:EnsemblMetazoa.
DR GO; GO:0034605; P:cellular response to heat; IEA:EnsemblMetazoa.
DR GO; GO:0008340; P:determination of adult lifespan; IEA:EnsemblMetazoa.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:EnsemblMetazoa.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:EnsemblMetazoa.
DR GO; GO:0045138; P:nematode male tail tip morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:EnsemblMetazoa.
DR GO; GO:0048337; P:positive regulation of mesodermal cell fate specification; IEA:EnsemblMetazoa.
DR GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:EnsemblMetazoa.
DR GO; GO:1900182; P:positive regulation of protein localization to nucleus; IEA:EnsemblMetazoa.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45944; SCHNURRI, ISOFORM F; 1.
DR PANTHER; PTHR45944:SF2; SCHNURRI, ISOFORM F; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 1612..1639
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1640..1664
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1863..1890
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1897..1920
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1971..2000
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 2328..2352
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 57..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1124..1162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1671..1711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1819..1844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2077..2097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2372..2391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2406..2426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 193..257
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 57..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1136..1162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1671..1692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2412..2426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2426 AA; 272790 MW; 3D1F94EC02CF015E CRC64;
MAFAPGSGGG GGAPQGQQQA QIMIPPNIPA EAYLRLTQQQ REQLNQQRLL QAQLQTNGPG
GLAHQQQQQR QNQERNQQQQ ASQQHQHQQQ MHHVQQQQQQ QREIQQRELQ QREQQQKELH
QRELQQREHQ QQQQQQNPQQ NQQQLQVNAQ LLQALATPQG QSLVNMLLIQ QALQAQQAQQ
NQGQTPQQQL LQQQLAQQQA QQLAQQQAQQ QAQQQLAQQQ AQQQARQQAE QQAQARIQAE
QQARQHAEQQ ARLQAEQLVT ERLQAQNIRD VNPEQFAQMV AYYQQMQRDQ QQQQIQLREQ
RQKEQLQQQQ LQQQHHREQL QQQQLREVLQ RQQTPAPQQV QHQMQQLTQQ QQQQLQQAQQ
QQLQQLQQQQ AQHQQQQLQQ LQLQQLMQQQ LQQQQQRAQQ TQNQGHATQR PSVASTPLPG
ASTPQLAEQL ALQAQLQQQL QQQQQLQQQQ QLLQQAQLQA QQQAQQQAQQ QAQQQAQQQA
QQQAQQLAQQ QLAQQQAQQQ AQQQARQQAE QRIQTPQGKT VSQALQYIQS MQMQQGTEGT
SNNAESQEEM LAQMLNEQQQ QMLQNQAREA QHRQMLISST PAPRGGLTMG TPIGIVRREA
STPATLSSLP VVTTTASRVA VRTPIAVQPI KQNSNPSILP SSASASASGS HQILASSLSK
SFDQPSTSKA SSGSGGNESM SDHISRIISE NEVILQGDPH SNFSTLTGST RTSPGPKDSR
MLQAASRSQS LFELSGSKHF MGSLTSGQPL LRSIQTHNDP NYTPECIYCK LTFPNEAGLQ
AHEVVCGKKR EFEKAQQAAA ENNPHSALKR RHTHQDATFA MNSPLAAATP SSMPGPSEPV
KKMRKEDSFD DDNSPSTSDG TRSSFPKSLP KEWEKHMLTL NNLASIIPPF VQAFLAKAIQ
SETLTLSPGA LQHIYDKYNI SPIAIQQFLH FASQLNNRQL EEIIAECEKL YLRNAEEWTN
QGIVSSLIQP LPADDLEIVE MIKQQDALGK GQVPELLVST FAILDHCSRR RDITDPAMNH
VVIKLLHANG KDITDVPMRA FNTLDGCNDR FISHMRELHK LNDVNDRLLN ALKTDPQATT
TPLFHVVNEQ SACLKFLLRE YGMVHLTIIA SVAKILGISS QENDGVDEVE GEEEEQQPGC
SQNGQTDHNG QNGQNDQNGE NGTVAFNGVV IKQEIVTPPP EYKNDDDSDD DCIIEVIDED
QQRQIDMAAA AARNNRNAAP MSFLDPDQDE KKPPKMMLQQ MQQQFAGGSQ MGNQGAGYTG
GQVDGQEIKK ELLVPKNEEP SQQEVVAMSL PLRLEDLRLE PQTSGDTDKP YWLVIDGDIG
GRPSFMAAGT QSRANRTRNI TSETYVTVPR QQPTFAEQDG TYSMYANWAT PVHNDAETKM
NLSFMGMVSL RRRTGQHEFW KYTTANKDLG HYRMTHSSFW DISTKIRDRQ ASMSDEKPLE
ETQDYDAQFI ERLVGGNYTA SDLQSSSTST IAIPILMAPE ETSSDQPGPS RLPPLLMRSP
RPVTPKLSIP QVEEAKQQEV IVPVSEEVAQ INEILTAPVE VPTKHESDVE VNMEKSPEAR
PSVIINDDVG RFRRDRPVKY VSRIRPKHDQ IIGGHRTDEV YVYVRGRGRG RYICDRCGIR
CKKPSMLKKH IKSHTDVRAF NCTACNFSFK TKGNLTKHLS SKTHLRRISN IQAGNESDGT
TPSTSSMMNM DEGYHKNQPL FDDYDNNSSD EEDYDHLNGM QAEHKFKFGQ EHILMERNAH
TPPTRWCLIE AENDHYWPSP DRRNCSSAPP VAMQRDFDDR AMTPISGASS PFPNALARSP
FSSISPRSRL VSENQFNDSA FSSASQTDEP SSSQNLNFHG HSSSHTNNLM TSNVNFFKKD
DEWRCDECDR TFRKEYEMTL HKHTHNIELQ QSKNRMYQCN ECRMLFRTKA LCSKHLEKTH
GHNVRLVLCL LMHLSDREIF QMDDSMITCI DPLATTQSVL GGPSTSNPRS FMCVDCDIGF
RKHGILAKHL RSKTHVMKLE SLQRLPVDTL SLITKKDNGA CLNDIDTTDC ERARISLLTI
VEKLRSERDR EESSSAQPSV ALKPDLLRAL AANTPQLPAA TAPSSSDTPP ISQSLPVGVA
SSSTSVSAVS ATGSPSNVSC VSSFNNSTMS PSPTVIPQVF LTPQPQSLSE LCSTHFIEKS
MTPEIEISIK QLNNSPKPIL RIPEVPAIVN SQLEIEPSTP PAQLAKHLHF SHSANTSPVM
SSPAIFIQRK RSESSLDNPG PTLVKQAKVW NPPPPEPAVV AQQQVFISPA SELCSTPETM
TIRPHANRPK PIPDTTNCPI CHHDLPNPIE LQTHIHVDHF QMRDGAEYRC PRRFCGLNYE
TIERLRTHVR NHYLSDYQKL LEERILLTDV VYPSEDPTPE TPSSPKKDEV TCNKYTTPFK
LISDHHEVYT DDMGPSTSSQ SPKTSN
//
