ID   E3M6V2_CAERE            Unreviewed;       541 AA.
AC   E3M6V2;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
GN   Name=Cre-glt-7 {ECO:0000313|EMBL:EFO93147.1};
GN   ORFNames=CRE_10197 {ECO:0000313|EMBL:EFO93147.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC       ECO:0000256|RuleBase:RU361216}.
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DR   EMBL; DS268426; EFO93147.1; -; Genomic_DNA.
DR   RefSeq; XP_003108347.1; XM_003108299.1.
DR   AlphaFoldDB; E3M6V2; -.
DR   STRING; 31234.E3M6V2; -.
DR   EnsemblMetazoa; CRE10197.1; CRE10197.1; WBGene00059485.
DR   eggNOG; KOG3787; Eukaryota.
DR   HOGENOM; CLU_019375_3_2_1; -.
DR   InParanoid; E3M6V2; -.
DR   OMA; ICVTATF; -.
DR   OrthoDB; 49426at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR11958:SF17; AMINO ACID TRANSPORTER; 1.
DR   PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT   TRANSMEM        43..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        77..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        193..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        235..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        268..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        375..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        400..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
SQ   SEQUENCE   541 AA;  59459 MW;  BC9136C883E110BE CRC64;
     MKENQLLVFT LSAVGTGFCV GIFLRQFDLS DGVRNLVGFP GEIFMQVLKL MVLPLIFSSL
     ISSLGQMDAS KSGKMSLIAV SYYLTTVIIA CFIAMIIAFL FHPGNPELKK QNDTIVRDES
     HLSALDSLLD LVRNMFPQNI VEATMYRSQT AFVVVRKKII KNGTTAEPVL LRKTIKLTQG
     TNILGETSLI KQLLIASSGL IVFCTGFGII ISKLGGKVKV IVEFFIVLDK VVMKFISVLM
     WFSPVGIISL IAASILDIDD VYVMITTMLL YLFTVMTCLF LHCVVAIPVL YFFITKKNPI
     HVAKGMIQPF VTAIGTASSG ASLPQAISSV EENLHIDSRI AGFIMPLGNT INMDGNALYE
     AVAVIFIAQI NNIHLSFAQV ITICVTATFA SIGLNAVPAG LVSMFVILST VNLPVSDISL
     LFTVDWFIDR VRTALNVLGD AYCACVVQHF MESDLAREKN EKLWEDLKLE EGTSEDANRP
     DQLEGKRMVK RVSFVDYHHI PSPSAPQAFN STKTYSLKSA IIGPLRAHVA LQTRLSHLSE
     E
//