ID E3MBP5_CAERE Unreviewed; 338 AA.
AC E3MBP5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CRE_16079 {ECO:0000313|EMBL:EFO97908.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993}.
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DR EMBL; DS268433; EFO97908.1; -; Genomic_DNA.
DR RefSeq; XP_003106606.1; XM_003106558.1.
DR AlphaFoldDB; E3MBP5; -.
DR STRING; 31234.E3MBP5; -.
DR EnsemblMetazoa; CRE16079.1; CRE16079.1; WBGene00061067.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_0_0_1; -.
DR InParanoid; E3MBP5; -.
DR OrthoDB; 3041044at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06960; NR_DBD_HNF4A; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR049636; HNF4-like_DBD.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46587; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR PANTHER; PTHR46587:SF8; NUCLEAR RECEPTOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..80
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 88..338
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 338 AA; 39155 MW; 2E5188FC70EF3FA1 CRC64;
MSIPSNLCKV CGDRAYSGRY GALACGGCNI FFRRAFLQKK YFSCSRDRKC VVYYTNRISC
RSCRLQKCLH VGMSVDAFKI RGHLTSPLTE NLLVTLTKLQ MIQFAEHYQY FKDHNVDIAF
RVANVRHRRR ARTRDANISL QLSLKHATEW CNMLRPFKKL STETKNHFLA EYFIAFMLID
QGYKTAKQTD RNIWLLHNES FVHLGTESSK SVLLFIINYI RFCFRNHFLH SIANPFHMLK
VDKKECAALK TILILKPSCI SPKIYYGQES AIACLYNECM NELMRHSLGR GGAIRFGEIV
LLLSAIRCGV KDVYNSMREP GFFDFESLSE NVRNVLLE
//
