ID E3MHU4_CAERE Unreviewed; 1504 AA.
AC E3MHU4;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFP02138.1};
GN ORFNames=CRE_25005 {ECO:0000313|EMBL:EFP02138.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
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DR EMBL; DS268446; EFP02138.1; -; Genomic_DNA.
DR RefSeq; XP_003104216.1; XM_003104168.1.
DR STRING; 31234.E3MHU4; -.
DR EnsemblMetazoa; CRE25005.1; CRE25005.1; WBGene00062191.
DR eggNOG; KOG1245; Eukaryota.
DR eggNOG; KOG2342; Eukaryota.
DR HOGENOM; CLU_002479_0_0_1; -.
DR InParanoid; E3MHU4; -.
DR OMA; CEATGKD; -.
DR OrthoDB; 1382023at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047171; BAZ1A.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR008551; TANGO2.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46510; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR PANTHER; PTHR46510:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF05742; TANGO2; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 22..131
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 473..540
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 1409..1484
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 265..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1158..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 416..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 278..300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1340..1369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1504 AA; 173592 MW; 360AE97DBAD9EC42 CRC64;
MPLLNKQPFI PRPVPDGTTR ETRLWHCKPT GEFFASHEDF FKRMILLNTT SWSCSMTRKS
NLTYFEAVQS EKEAEKELIE FPESLELPIL FITHKYTNRG RFEELVNDIY HIMKDRFFMN
EEVTFNEKTR KLTARIVTSY CTQQQILDAN GMEVEIGHEI KEPLLPGADS YRYTIEILEQ
GLSEGDKFRE HISNEKLFRS KNVGARQKIR LFLKNSCHLP PDGDRYTIRD CFIPKVESLW
WSDVMSGSEP MCPQTPVLQR GRIPNMLKNG EDVGGGAAGA GERKERTPKR EKRDPSAPPR
PRGRPPKTPE QRALAQQEKK QRKRAEAPPP GPDDFDLTSS GALTFHGHPM TSSSSPAKKK
IRRSSTSKNE KKKAKIIEQQ GDLDFYFTEA RRLGIDVTGL EQDEKLLSPK KVAEFKMRVK
EEKDVEREAL KEEKKRKIRE KAAYNKKRED LLCNDLKPMP KFPSLEIPTW MSDEEFGDFL
FIMQFFSTFK EILPLKEIRG NDEIQFSDIV LAVKCNDPQN SPFADLMRVL LSIRTDIADE
EDGDEADFSN RDEIYLINAQ NCDPANVVYG ESIREISDLH FKIRKIHGKS VRHLPVDWMT
LTEVLRLIFE TSGYYTGIST HRHRLYARGN YRGYEDPAFE FRHAHPQIME KLRTQTVFDL
EPSERLEIMK TLIYQLLTYS KFRIHLEKHQ MELTELRKEQ KRLKTWDAGQ EADSNAARLL
MEYDSQSGGG GGGGVKDVEK EALVKRFKTY LKALNEGRRY DKEDLDTILL DAVPYTSLTL
DEIVTARDLQ KAEFKTLMQS ITSKLFSTYC KVSDIRLGSD RAYRRYIVID KLSAILVENP
TSSELRIECD EPSVLEVSED SESHDVFRCT GHLESCEVHG ATRDSKTRWS YIKNREQFDE
FVGSLNSRGL REHEMLEELQ EYRLNLLELL EDTEDALGDA TWQENLMTEE TDPADSYNID
WDAEIRDLLL DFEEKLDQGQ MGSIEKKFKI SRPAWREKLK ENGDVSGVLT ENLKIFDEDV
VEMDDVIGMS DSRKLAIAFF MIIRSIQLKF IKPPFISPNR DEHGNLKPSE LFIRWQRALL
QTDSHSALSL FISTFEGAIK WDKSRLQGKC KSCRRKAVAH ELILCSECDN CYHLKCAKLA
EPEDDWMCTT CRAQHRKTEN EAKRMAREEL NNISINETDL SSSESQETPS TSSEQQPTTS
MIKTASGRSV KKVHYSEVHE GLSLKSRKSN GMVAAAATPT TPSERPHRNV TMRNSEYHVI
SNSPLTKPYQ KAIYGRRLIS ERLRDSNEMS VEQVFENLMS IATDKTHCYP DAQLQSHTQN
TDEYHQSLSA IFIKYPERTR DYDTDNENNH SDDDEGTSDA SDGENTRKRK IPAAAAVAKS
KSLVDSPRVI IPTTKEKMSS IESLLKEAMR QECSWPFLQP VDPKEVPDYY DVIERPMDLR
TMMNKIKQRV YNKPAEVREE MIRVDFEQIL TNCETYNETE SEIYQLSREL QDFVTARLDA
IIGQ
//
