ID E3MID3_CAERE Unreviewed; 3115 AA.
AC E3MID3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=CRE_01012 {ECO:0000313|EMBL:EFP02416.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
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DR EMBL; DS268447; EFP02416.1; -; Genomic_DNA.
DR RefSeq; XP_003104155.1; XM_003104107.1.
DR STRING; 31234.E3MID3; -.
DR EnsemblMetazoa; CRE01012.1; CRE01012.1; WBGene00063047.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_0_2_1; -.
DR InParanoid; E3MID3; -.
DR OMA; RTLKVHW; -.
DR OrthoDB; 2882674at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 3.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 5.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 1339..1414
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1790..1865
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2807..2882
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 263..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3115 AA; 358371 MW; 10BED345795D1566 CRC64;
MNSKNESFFC EVLPEVCRVY EQKRFADSLN IYVSDLKFGH SESVEKSDDE TEIRTKEGIC
VATFENCKAV KQKRMTETDE MMFGIFGIES MKTSDIPPEV SALNARLILP KASDQYVSHV
EIRNYEIPLN PSFQDIFYCS PSEIKLCQKE KNEIYLHVNL EKEYQTSRTA LFEGILLMLE
ELKVKKEIKR IKVLCIPFVH FGKVRICVTL DEKTKDIRVE IFNSFGSLFG FIEIPENESR
RNREIEEKEE LFLTEKMLRI KYSTEDENSE ESEKESEETS DIPNASGVSL TLNFLITILQ
NKMNLLKPLT DGVSFTPLPY LGVDSLRLAE LEFHIANSQE FKKCQLKPPY LIPFKTLSQV
AEFLDMKRKE ITRNGILPSV TTFVSNNSKV PDIEKEQIYF HEIHSKFRIP LSCQQKRILF
IREFEKEYLN PTTFSQFDES VLLHFSIFQN DRVTEILNSL IMIHSILRTQ YEEDFQFILS
GTECFVMIKY EERDISYCHN LNVVTAIQCC LRSDQYLHIT FNHISIDGRS LQIFYRQFKE
MLSSRRSNRQ KSPLQYRDYC RSNFTTSTEC LKYWKKYLNL EQIELEKLPS DFPGLSDFSA
SSYIYKSFPT RLQRKFDDFC HQFSFSRFEL FLGILEISLH RVFGVSAPFL IGFAVDLRTF
PYFETIGCFT NVLLYISLNF STNQLTNQLK NCQKSLRETR SHGDIPYESL VKLLGTEGNL
FQVFVVSDIV ETDLTSEVIS RSERRVRFED ETIIVEIVQD SEDSQEKERK KIAKYPMTFY
LRQFGNGQLQ IEVEYASELF KSETIDSILE EMFRIVNSMS SVSKDQKTQS LLNRFTERKP
YKRSDFPSST VSQIIFSNNS KCDIRYLQKN SSVHPNEFSS FLLKNHMKMY CQLLNEYPIL
INIPRSPDLI LATLGAWKSG FYPVPLHRDA TNEQIQKTCD GLGLKMEGTA ILRNLDNFNS
IKIKQAFARR QIFNRTALFD FAYVTSTSGS TGTPKLVGTS FEGHSNLARQ YTTSFQLSSR
DIIGQVVDPS FDIFFADIVK TFTNGARLLL SRDSIPTSSE LLECSNVYLM PAFISRLPDL
KCLNNLETLQ YGGEPIASQF LKLTHQNNKE LNVWQEFGLT EQTVYSTRKK IRPLDIYNSE
EIKMIGDPYD NIQIEVNSFS GSNNSSENCI RGQLVLKGIG LMRGYFDVTK CVLDQFNTGD
EVRKLKNGDI VFIGRKDLQV KIRGHRVDLF EIECTALSSK LLEYCSCIAI GNQKIILFYK
LKSSNNDQDQ LSKFIDYLEK QLLSYKMPSQ LIPLSSFPLT RTGKIDKKQL ANMVMNSENS
CEIVREQKEI RNIILNQNDD RTGKLHDLLK KWLQHYSNGT IKSIDDNIFS DGIDSISVML
TMQKMRSAEI EIPVKMFFKL KTIRKIVDWV LETPQSSEDA KEVLESKTVI KEKHIPNHYI
NLNHIQQRIL FLSRMSFSKS NSNNSFYSQF SIELPSVPVS HCVLLQCVNT IIMGNRMLRS
KLQRIQGEYR FILLSGTECF YRTQLDSHFN SHSYIDPFVT RIWSDKNETR LFILIHHIIF
DGRSLQILEE QMKQTLKNGN NEILFQNVFC CEMNQIPRHL FIDLQSWKSM FPSFLIGSES
SRIEFNLSFE NNLEAIPVAF KISHAYCMAI CKVFQISTSF PIATTFVNRT ENNWNTVSMF
ANTLPLMYYP EQDLHQFCER FFELAENSNV PLNEVLTRGS SGVGNFADFA FNSHKSIGNN
RENNGVCQFP MVLTVSETEN LARIEFDNDY ISQETAENLR NEILKLLGCG RAEHHERVNF
VEVFQLFLNS KVSENTDFFH SGGHSLTAMK LIDYLSDLIG IEVPLKLIFE FRTPKKLETA
VNSLKVNRDP VATIMDKTVP KVTEKSFPRA LSSEGTQSFL KETETFKFPL SRQQEQMFYL
AQLTSASLEY QLPFIQPFPS TVSPSEIHRS LLMTIQEQNI FRTLFKMDPE TGEPYQEVVS
MTESFIRCHV ESVQNEEKLH QTIRELCEEP IDVLSGHCLL KASFVTSSQK HIAFLHLHHL
ISDAKSTQLT NSTMKSFFDD SKKMAKRLKF TYLDYCSLEQ GIRSNKIDND YLKTLVNGLE
GLNIGKGERM DPVKVFIDIP KQLISDRLIN GKPGDTPFSL LLKMFSSSFT SQGQNFNIAF
PVLNRNEKTS SLCGYFLNNL VINTDHLSEL PSILNNNLPY SEVMREVRRI SGTNLSIADV
YVNCRYDLEY DESDDEILLN LVPLKLHFPV EIDVDLMANQ TYRITMRSNK ISENEIIRML
NKLKKDFAVV RKAQRNEKIV QSGENTLYGA RKDVPSFPIP ELYEKIFNSN FTSTFATSSV
NSESLSYCQA YQNILRISQK LSRDFLVCRG IPIRSDDVIA VIGSKSIETT IKCLAVQFAG
AAYLPIDEVY PQKRKREIMR DSVFCFKESK VLTGNSKLVS NRQRRYSIST PFCLSYIIST
SGTTGNPKSV AIGADSLSNL CVSSTITMRV SSSSRIFQFT NFVFDNSVLE VSMAISSQAS
LIYGSPNFDP FEFGNLVENV GITHCLLFPS LVQSFEIERI KSLPYWIVGG ERLPRDLLNS
ALKTGIRVIQ NYGPTETTAF AIAKQMKHGD FGCCIGYPAI NTKGRITIKE SGDQGELLIS
GKGIMRGYLN RQPSEYLKII DEISWYSSRD KCRITPNSGV QFIGRTDSQV SWMVYRNFSS
IMLFQVKVRG YRIELSEIER TIECHPDVIA CKAIFEQESQ QIHVFYTGNA IVSSSEVVRK
RCEQLLEPQK VPSTFNGIKE FPLTNNSKID KKKLMEIVKN SHVPNISETC PLETELSSIW
MSLLNCSKPS SSDHFFLVGG HSLLLIRLRH LIETKLKVHL SVPEILENLK FEEMLQIIRN
KKDFLERKKR RTVVFFPGLY GGCTAYLKMI GQLKNSKEDI ENIILLEEVL GNSVQEVASQ
YKTQIEEKVI DRISSYVFIG ASSAGTFAFA TSNQFEKEYD IIVILLDSGT FWNRIEKLDY
SKHESVSYIL FDFDLFIFQD MMENLKNYEV DKGTANRMAE SSWKNLQILK NYQPEIDTNS
RKINVLSVDG SDLGWSKYSK NSKNFKIPGD HYSMLQDPEH LSDVLKIIEK IIRDQ
//
