ID E3MMQ8_CAERE Unreviewed; 964 AA.
AC E3MMQ8;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=CRE-MGL-1 protein {ECO:0000313|EMBL:EFP04998.1};
GN Name=Cre-mgl-1 {ECO:0000313|EMBL:EFP04998.1};
GN ORFNames=CRE_03212 {ECO:0000313|EMBL:EFP04998.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS268457; EFP04998.1; -; Genomic_DNA.
DR RefSeq; XP_003102611.1; XM_003102563.1.
DR AlphaFoldDB; E3MMQ8; -.
DR STRING; 31234.E3MMQ8; -.
DR EnsemblMetazoa; CRE03212.1; CRE03212.1; WBGene00063152.
DR eggNOG; KOG1056; Eukaryota.
DR HOGENOM; CLU_005389_0_0_1; -.
DR InParanoid; E3MMQ8; -.
DR OMA; AFERNKW; -.
DR OrthoDB; 1331864at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd06362; PBP1_mGluR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF158; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 652..675
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 719..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 820..842
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 862..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 650..908
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 939..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 948..964
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 964 AA; 109440 MW; 17B30EBD36702480 CRC64;
MFSVLALATQ ILANVNVIAQ TAETISLAPP AKVRQIRIPG DILIGGVFPV HSKSLNGDEP
CGEIAETRGV HRVEAMLYAL DQINSQNDFL RGYKLGALIL DSCSNPAYAL NQSLDFVRDM
IGSSEASDYV CLDGSDPNVK KQSQKKNVAA VVGGSYSSVS VQLANLLRLF RIAQVSPAST
NADLSDKNRF EYFARTVPSD DYQAMAMVEI AVRFKWSYVS LVYSADEYGE LGADAFKKEA
RKKGICIALE ERIQNKKESF TESINNLVQK LQPEKNVGAT VVVLFVGTEY IPDILRYTAE
RMKLTSGAKK RIIWLASESW DRNNDKYTAG DNRLAAQGAI VLMLASQKVP SFEEYFMSLH
PGTEAFERNK WLRELWQVKY KCEFDIPPGT KGTRCEDIKQ STEGFNADDK VQFVIDAVYA
IAHGLQVLKH LFFITKSNFK SMKQAVCPDD AIENHWISRY SKQPEICHAM QNIDGSDFYQ
NYLLKVNFTG ESFISIFFSH ILLFEDIVGK RFRFSPQGDG PASYTILTYK PKTMEKKRRM
TDDESSPSDY VEIGHWSENN LTIYEKNLWW DPDHTPVSLC SLPCKIGFRK QLIKDEQCCW
ACSKCEDYEY LINETHCVAC EQGWWPTKDR KGCFDLSLSQ LKYMRWRSMY SLVPMILAVV
GIIATLFVIV VYVIYNETPV VKASGRELSY ILLISMIMCY CMTFVLLSKP SAIVCAIKRT
GIGFAFSCLY SAMFVKTNRI FRIFNTRSAQ RPRFISPISQ IFRVFSGWRH HYPTRDQVVL
TCNVPDHHFL YSLAYDGFLI VLCTTYAVKT RKVPENFNET KFIGFSMYTT CVVWLSWIFF
FFGTGSDFQV YAVPQNNDLQ MFQIQTSSLC ISISMSANVA LACIFSPKLW IILFEKHKNV
RKQEGEIMLN KSSRSLGNCS SRLCANSIDE PNQYTALLTD STRRRSSRKT SQPTSTSSAQ
DTFL
//
