ID E3MR09_CAERE Unreviewed; 703 AA.
AC E3MR09;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN ORFNames=CRE_13507 {ECO:0000313|EMBL:EFP07285.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS268468; EFP07285.1; -; Genomic_DNA.
DR RefSeq; XP_003101431.1; XM_003101383.1.
DR AlphaFoldDB; E3MR09; -.
DR STRING; 31234.E3MR09; -.
DR EnsemblMetazoa; CRE13507.1; CRE13507.1; WBGene00063993.
DR eggNOG; KOG1056; Eukaryota.
DR HOGENOM; CLU_005389_0_2_1; -.
DR InParanoid; E3MR09; -.
DR OMA; VANTEIW; -.
DR OrthoDB; 1331864at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15934; 7tmC_mGluRs_group2_3; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF171; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 274..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 274..536
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 560..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 78795 MW; 2F692C0557B1B3E6 CRC64;
MIFRKFVASD SWGIKQSVVR GLEHRTYGAI TIAPMVREET GYLEYFRSLS PKGFVFLEEF
FEYLGCSATE DIKTFGDCFD MVNVTLKQES YVPFVVDTVK IIAKAISMYI EDDCGKTPFH
KCSLAQSGFR GERLQRYYRN MSLNKNEPAL IDANGDGIGR YDVFQLDMNG IYQKVGKWRS
TDDFLSVEVE KIRHAFKTAH GERPMSVCST DCPRGHYRAY QDQTCCWACI PCDTSTSIHN
ETSCEECAIG MVPDRTLHFC VPIPPVSMQW DTTWSLIPAA FSTLGIASTI FVVSVFLKFS
NTPVIMASGR ELCYCMMSGI GMCYVLTFFL VSQPTVITCS LTRILMGLSM SAIYAAIITK
TNRLARVFKP DSAQRPRFIT PKAQVGICMG IVSVQLIGTF VWLFFDPPGT MIVFPSRTEA
VLTCKATTSH LLISLLYNIL LIVACTVYAF KTRKIPENFN ETRHIGFTMY STCILWLAFG
PIYFATQSDF RIQITSLCMC ISLSGTVALI CFFAPKVYIV LFQPYKNVRT RQSAVGRLVN
QQMRFMSQLT YNPDGCNSYQ PMSSNQSYKP STEESSHTSN APGLPQTRAI PPHVIEQLAA
SLPISDKNDL VKKLSLQDKL LNNNNNNESS EEIRRRRPSS VHTVGAIANG ASVAHIPPRS
YTDEPKSSMI RQDTTKSRAS LAESHQVDLI LEEIAADTNS TFL
//
