ID E3MSZ0_CAERE Unreviewed; 1204 AA.
AC E3MSZ0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=CRE-NLR-1 protein {ECO:0000313|EMBL:EFP08488.1};
GN Name=Cre-nlr-1 {ECO:0000313|EMBL:EFP08488.1};
GN ORFNames=CRE_15562 {ECO:0000313|EMBL:EFP08488.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DS268474; EFP08488.1; -; Genomic_DNA.
DR RefSeq; XP_003100723.1; XM_003100675.1.
DR AlphaFoldDB; E3MSZ0; -.
DR STRING; 31234.E3MSZ0; -.
DR EnsemblMetazoa; CRE15562.1; CRE15562.1; WBGene00066289.
DR eggNOG; KOG3516; Eukaryota.
DR HOGENOM; CLU_273234_0_0_1; -.
DR InParanoid; E3MSZ0; -.
DR OMA; TCHTSMY; -.
DR OrthoDB; 4255614at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF89; NEUREXIN 1, ISOFORM F; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1204
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003177614"
FT TRANSMEM 1136..1158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..293
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 447..484
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 714..882
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 878..915
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 474..483
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1204 AA; 133974 MW; F1159EC5C198F872 CRC64;
MRRRGLCLLF LIFTNYAVSQ SSAECSDVSF SSVASKLDGL KRVTRLSVSG HISAYHVKVS
ISDDDFQLVR VSNGNPLVLY STLSNTPSWT HVDFLASEVK ILPAFEQATE DVRGPLLILT
VCDYDTPITA FDDSSYTVEA HHAGLVSMYE NDLCVVFRTY RSGVFFFSMA DQGDVLIAQI
VHGTIHVIFD FGSLTPSRIS AGKALDDGRW HEMRWLHQFD SVQLSIDGVL LNQTAPTGLY
RKLDLHSVVH IGGRPADDFS QGIETTFTGC IARLQLNNAD LLQLSPSEVH SQCQMPKPPS
FTLHNSSQAV LPFTFLPFSF EFRIVPVNGP LVTLLDAENG TLVDVVVDDE RKLHLVSNIT
KFKQAANPAI DVANGGWHSF SLRIRGVRME IDIDGYTVLW LEGHEVRRIS QRLSNFILSA
SGCYRSATID LTSVRVDGNV TRGECSFQEK CLPNPCENGG ECVQSALDDY VCNCKDGYKG
KNCHTSELIY DLFLILIPLF SADLPHSCEE WVFTKGNKQK AVQGRKVLID VDGGGEMQPI
NVTCKTERDE LGIDGVSTIL EHDLVRPMIV TGDNKPGAVR YSLTYGISTE QMDRLVEGFE
ACSQFMRYTC RGGVRLMTQG DERSPSSWYS TRSDKHGLQW GEAPPYSRMC SCAINGSCLH
NRMCNCDSGE DATDEGVNPY SQLLPVTGLF LGGTTKSSSI EVEIGPLKCR NRATFDPVTF
SDRNAKLSGT QTFNQRTFDV SLHVKFSHSQ MSILSWHSTD DLHWFHLYVN DGKIVGEVVN
GGESQQIVSE HRYDDGKFHA IYWEADSTGM FLKVDGQRKS LKTSFVLPTV YTWIVGSRTE
KGSTGFAGVI RNVYLCGVEL ALGQYARKET ERGIAVGDDG YCRPDLCQNG GQCIDKYDGY
VCDCSMTPFG GSDCTKEYGM MVPAGSSIQI PWQNPAHQSM CHRIAIQTTS KNTTILRSKA
LFADSTFNMT VDDNGNLQMN AYDGFFFHFK RHSKHHNLSD DVMHDISFCA SKHHFNVSVD
GMQVITIEGN WTFFESFNVW HFLDESMLQC LFSDFEGCVS RIQTGSAFPL KSPKTARLNY
SGKIRFGTCP IEAVSRHQMY DFNPQPEAAS STVATSTEDI KIFSVSQSKQ DLMSKAIVFG
GIFAIFMCIV CMSSLICYMR SRPEGVYKTN ETGENCSPSR SEEPLVHNVN NNTPMYASNK
EYFC
//
