ID E3NB50_CAERE Unreviewed; 377 AA.
AC E3NB50;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFO91800.1};
GN ORFNames=CRE_07792 {ECO:0000313|EMBL:EFO91800.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; DS268582; EFO91800.1; -; Genomic_DNA.
DR RefSeq; XP_003094346.1; XM_003094298.1.
DR AlphaFoldDB; E3NB50; -.
DR STRING; 31234.E3NB50; -.
DR MEROPS; C01.A37; -.
DR EnsemblMetazoa; CRE07792.1; CRE07792.1; WBGene00069807.
DR GeneID; 9812957; -.
DR KEGG; crq:GCK72_022035; -.
DR CTD; 9812957; -.
DR eggNOG; KOG1543; Eukaryota.
DR HOGENOM; CLU_012184_1_3_1; -.
DR InParanoid; E3NB50; -.
DR OMA; CGTRMNH; -.
DR OrthoDB; 5602104at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF966; PROTEIN CBG12926; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..377
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018772318"
FT DOMAIN 39..99
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 137..370
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 377 AA; 43229 MW; E2320C7168CAD2A6 CRC64;
MYLILVLPFL FALSKCLEVP EFFEINIDRD HPDNIYKAFE EFKVKYNRKY KNAAENQIRM
QNFVKTYNKV DSLNKRSEEK GLTSQFGINK FSDLSSQEFK RRLLSSTHGN ITGFLKNSRK
LTFPRRHKRQ AEMSEDLPES LDLRTETVNG RYIIGDVKDQ GECSTCWVFA VTAVVETILA
HSLGRFKSLS EQELCDCATD GTPGCRGGSL HWGVEYILGK GLAGAWEYPE YNQQRANKSG
MCEAASSKRS FPPNKLEFYD LSENPEYEMR GVLKFWKSPV AVFFQVGTSF RNYRSGVLTY
EDDCRTGPEI HWHAGAVVGY GEDRDRYGRS QKYWIVKNSW GTGQWGDDGY VKVIRGRNWC
DIERGAVGAK MTDSIHS
//
