ID   E3NDC3_CAERE            Unreviewed;      1604 AA.
AC   E3NDC3;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   RecName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CRE_02635 {ECO:0000313|EMBL:EFO93556.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS268608; EFO93556.1; -; Genomic_DNA.
DR   RefSeq; XP_003093587.1; XM_003093539.1.
DR   STRING; 31234.E3NDC3; -.
DR   EnsemblMetazoa; CRE02635.1; CRE02635.1; WBGene00068897.
DR   eggNOG; ENOG502QR81; Eukaryota.
DR   HOGENOM; CLU_002807_0_0_1; -.
DR   InParanoid; E3NDC3; -.
DR   OMA; HITESYT; -.
DR   OrthoDB; 2875525at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd00047; PTPc; 2.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR003125; WSN.
DR   PANTHER; PTHR32525; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR   PANTHER; PTHR32525:SF1; PROTEIN-TYROSINE-PHOSPHATASE-RELATED; 1.
DR   Pfam; PF02206; WSN; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 2.
DR   SMART; SM00404; PTPc_motif; 2.
DR   SMART; SM00453; WSN; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..1604
FT                   /note="Tyrosine-protein phosphatase domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003178512"
FT   DOMAIN          962..1164
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          1337..1580
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          1516..1571
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          29..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          846..870
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1225..1272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1604 AA;  180449 MW;  54012B353F58B1FE CRC64;
     MKVFAFLSVA TATVIYATTS HRRYYASDNH RDYPNFFDDP RTSSGSRSAN SHSSSGSSPD
     SPSPGSPSDS SQPTNIRSVR SVSFPEHSED FSNPHIRTIR NVEESADYLK HTTILAHLVN
     GIALQHGLMN GTISPSDAVG ELLNFGSVAV SSIVNFKKDG INTLIEKLKS VKSDIDPNFK
     DYEKIALQWN EVILEVSKIG DVKNLTGIDS YLQVLEGFIK NFKFGSFEKP GNAFATGMTD
     LEYIKTLKPT NSDNFDKLST LKTHLKKAIS YVTDFKSCSE ELQKNYKSLE NGPAVFSPVE
     KTILLSKKRN FNKIIEKQYA GPVKKNIEAA VQVSKYAQDA QKDVLILNNL AESISAPGSI
     QRKYTNGFPN GLADLKPLLN DVRDRWIQEV INITGANPIV LTDGLEPLFR LQKRLEEMDD
     KLSPISTATN MNKALSDFKK LQKGLSDLKS ESVDLVEDLF EKLNSARFVP LYENSYEEIM
     KSIQTAKDLQ ELSDAAIEAM DGFDAEKLNK EIDKLFDSLG FKNFNDENGS KDEFGTVFED
     ITTNGKLKGI RDFIDGLNKR FRKISATTEG GLKKRVQQIF ANKDKINKFT GLDEEINKVH
     GYLKPLQNNS EKVSQAIKAY QQLRDIRLED IPVFETVASA ISDVAQDLSL VSTIPDEMKK
     DVSQATTEIN KLPDSLAKSV VIGHSVNSLR SAFALRDLKA EVEKLKTIDS AVQAVIQKIW
     GNYKEDMAEL EKTLGDIERF EKNLNVSNLT TIGAYGTPLT ALASLTSVNM NAKEKSKALE
     ALLNDGALKM DPTVKENIEK SKDTLDQLAD LDLGFASHTT QFQSAPGVFS DLQNFLTKLL
     QVPMSPRQPS GQVPGAQGGP GGADAIQQGQ KSDEEEKGLS WYYIALIVLF SLGGGGGAGV
     GFYLWHKRSQ WKKWLAKLLY WIRSNALRNV ESAITVHSNH VERIRLEARS WTPTENTVAV
     TRRRRADLQC NSDSAVLLPL VDKEKNVMIY ANKIKTKKGL KLIATQAPSI NTEFWMMVMQ
     ENSDFVISMC SDDEMTSLEC SYYPHKVNET VSYGPYSVCL KEEKLTASKK VKQRTLVVTD
     SSSKDKKTKT LTHLQSFNWP VDTILDDHTE SLEILDLVKD STTPIIVHCA DGGSKTMSLI
     GLQYVYEEVK DDPSKDFDDL VVEMCNKTWH SIKENVFTAW IASGVRIRLI TEFEFHNEEA
     SYTTDKEVLK KMKVALEEKR VADTKADEAR RLQAEQDEKD RADRENQQAE ADRIKDAEIK
     NLKDENEKKE AEKAQLVQQA EIDKAAALQR AEEERKEKER AELKKKIQQW IKKQRCTDIN
     KLFALHSGIL KAMDVGHRDK KKALDELPIP KHRFAFLCNP DTAVIVKSRG KRIPIHANHV
     KTDSNVRYIA AQAPMPKEEN RDDTCEDFWV MVLYENAEFI VNLCDELQTR VACGNYYSSE
     VGYVECGRFK VITKSVELIL EGAVKKRILE VTDNENEFKP AVIKHHQFLA WPDHGVPKGH
     DAALGLMNIV KESKVPIVVH CHAGVGRTCA FIGLQLVYEE ILKHPENSMI EPMYKLRDQR
     WNAVQTSSQS FWIYLGIVLR LIREYKLDMN DYTEQNAIFN IKMC
//