ID   E3NGS4_CAERE            Unreviewed;       756 AA.
AC   E3NGS4;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 55.
DE   RecName: Full=N-acetyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CRE_04342 {ECO:0000313|EMBL:EFO97212.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268658; EFO97212.1; -; Genomic_DNA.
DR   RefSeq; XP_003092411.1; XM_003092363.1.
DR   AlphaFoldDB; E3NGS4; -.
DR   STRING; 31234.E3NGS4; -.
DR   EnsemblMetazoa; CRE04342.1; CRE04342.1; WBGene00071504.
DR   eggNOG; KOG2132; Eukaryota.
DR   HOGENOM; CLU_016785_7_0_1; -.
DR   InParanoid; E3NGS4; -.
DR   OMA; FIEEQNC; -.
DR   OrthoDB; 11696at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR041667; Cupin_8.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR003347; JmjC_dom.
DR   PANTHER; PTHR12461:SF97; BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7-RELATED; 1.
DR   PANTHER; PTHR12461; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED; 1.
DR   Pfam; PF13673; Acetyltransf_10; 1.
DR   Pfam; PF13621; Cupin_8; 1.
DR   PRINTS; PR01217; PRICHEXTENSN.
DR   SMART; SM00558; JmjC; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51186; GNAT; 1.
DR   PROSITE; PS51184; JMJC; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        707..723
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        735..755
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..148
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   DOMAIN          459..618
FT                   /note="JmjC"
FT                   /evidence="ECO:0000259|PROSITE:PS51184"
FT   REGION          622..705
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        622..667
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        678..705
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  87149 MW;  B3E89A17D600DD3A CRC64;
     MEIKRLSIEE CREGVFDIRR KVFIEEQNCP EHMEWEEEEE RDSVYFVAFS GDRAVGCLRL
     RPVEQDLLKM ERVAVLKEFR RRRIATDLVR EAMIYVQTET PSSSIYAYAQ VTALQAYVSL
     GFTVLSKVWI EDETFIPHQT IFWGTPVSIS VFLKHQAEKS DVVYEEYDAR HPSVLPKIEA
     YKQRLENLET WNICSLHIHL EDRVVSKIIR NNFIKFCANS QEFLNGNHDL SSDIVKQSIN
     LLKIADAKLN TGHFNEVDEN WRKLYALVSF VQSFLLFRGK RADFENAIKI ADKGLCMGRI
     DEEIVPIRQL AWLIHEQLPG VSAPIHSSFS SFSSFSAEKT QNFLSPLPNS VPISECDDSD
     DDCLERVISA ISQGTPLLIR RHCMHMPAVR KWNIEFLLKE LHSRTFPVEI GTKYSDEDWS
     QKLMTFGEFV ENSEYRFSVK KSSKITFFQK KKHLQNQRLY LAQHRLFDQV PHLKRNVIIP
     DECFRESTNP DDVDMNMWIG PSNTVSPLHT DPRNNMFVQV HGTKLFRMVS PEDTSSVYPF
     DGILGNTSQV DVENPDATEF PEFSRIRRVF DGVVNAGDAL FIPKKWWHFE ALIVLCLSCL
     FVTPRYNTIA FFGGRVSAKP RPPFAKPRPP FPKPRPPFPK PRPPFAKPRP PFAKPRPPSA
     KPRPSFEKPR PPSAKPRPSF EKPRPPSAKP RPPFTKPRPP FAKPRPPPFP VIISVIILLF
     PVFHPHLRRE APPQLFSVSV PFSFMILGGL LTNIMT
//