ID E3NRS0_CAERE Unreviewed; 424 AA.
AC E3NRS0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFO88411.1};
GN ORFNames=CRE_15097 {ECO:0000313|EMBL:EFO88411.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993}.
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DR EMBL; DS269787; EFO88411.1; -; Genomic_DNA.
DR RefSeq; XP_003088901.1; XM_003088853.1.
DR AlphaFoldDB; E3NRS0; -.
DR STRING; 31234.E3NRS0; -.
DR EnsemblMetazoa; CRE15097.1; CRE15097.1; WBGene00074270.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_7_0_1; -.
DR InParanoid; E3NRS0; -.
DR OMA; DMKADYK; -.
DR OrthoDB; 2873905at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06960; NR_DBD_HNF4A; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR049636; HNF4-like_DBD.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45680; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR PANTHER; PTHR45680:SF30; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 24..100
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 143..419
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 424 AA; 49252 MW; 11ADBF2AA80557ED CRC64;
MMEIVPLNLQ TTLNLFAVPL PPPRTMCKIC GLPAHGVHFG VMACRACAAF FRRFVVLNLD
YECLKDKSKC SLNKIRRSSC RHCRFQKCLK MGMTADNVQW NRDVYSTDLR YKKIKTPEPK
NDENDLTIAL PSTSTCLYSL IKTQDQLYTK SVLSEINYDN IERDMHRMFM SDVPSTDHGY
FASLSPLYKI VEGLRLVRKS QRTADIKFEN RLSMETLVPH WRAQAKNTAI LSMHSMAFRD
IPLTEKSRIF KSLWQNIYRF ERIQMSTEIF GENCVSEKKL AISCERAIQL DSLFFDMKAD
YKAFAERCVE EVAKPLSQLK LSIEEVAYLI INFVLHNEEK IIGESFDICD KFRDSIADDL
HEYYRKNDIV NYASRITKMM NTIVAMKKIH YDDLGGTFVT NTRNAKEVEV KEEDDDEDEE
IIVD
//
