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Database: UniProt
Entry: E3NUJ8_CAERE
LinkDB: E3NUJ8_CAERE
Original site: E3NUJ8_CAERE 
ID   E3NUJ8_CAERE            Unreviewed;       801 AA.
AC   E3NUJ8;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   25-APR-2018, entry version 29.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=CRE_05360 {ECO:0000313|EMBL:EFO95669.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; DS270573; EFO95669.1; -; Genomic_DNA.
DR   RefSeq; XP_003087924.1; XM_003087876.1.
DR   STRING; 31234.CRE05360; -.
DR   EnsemblMetazoa; CRE05360; CRE05360; WBGene00062672.
DR   GeneID; 9816908; -.
DR   CTD; 9816908; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   InParanoid; E3NUJ8; -.
DR   OMA; WWIRRSA; -.
DR   OrthoDB; EOG091G01BI; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008281};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    446    469       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    616    637       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    649    669       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    681    704       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    738    757       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       91    111       {ECO:0000256|SAM:Coils}.
FT   COILED      130    157       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   801 AA;  91768 MW;  F262C814A455BC05 CRC64;
     MSTTTSISEP ILHQSAKINL TPPGKNPISS HQKKMSDKSD EISMFRSEPM KLYQMILVKE
     AAFECVAELG KHGNVQFIDL NAKLSLYSRS FVKQMRRCEE MERKLRFLEK QVITCKPGLD
     PKSIDFGDLS APTQAEMIQL EHKLDQLEKE FLDLNNNDYA LRRNLNSSRE FLHVMKLVDE
     FFQVEMFSKS FGFGGLPSSN ELPMTPLLGA DDNAWFVAGV LPLDKKESFE RVLWRACRRT
     AFVRTSDSHF LVNDPVTLEP LPKCVFIVFF KGESLRLIVE KVCDGFNATQ YPCPKSSKDR
     KMKMSETEGR MNDLTVVIDT TQTHRYTILK DLSYELPIWL KNIQIQKSVF GVMNMFTVDT
     NGFLAGECWI PAAAEENVRQ ALHDGFKASG TEVEPILNEL WTNAPPPTLH KTNKFTRVFQ
     SIVDSYGVGQ YREVNPAPYT IITFPFLFAI MFGDAAHGAI LLLAGLFFIK NERKIEAKKI
     RDEVKNINLF VKLKIMNFQI FNTFYGGRYI MMLMGLFSIY TGFLYNDAFA KSFNVFGSGW
     SNSYNTLGPS NFFHTYSETQ LDWWIARAYR KKREFALELV PEKSFDYEKT YPFGVDPIWN
     IADNRLSFLN SMKMKASVVI GITQMTFGVF LSVLNHIHFK SYIDVITNFI PQVIFLSCIF
     IYLCIQIIVK WIFFNVNAGD ILGYAYPGSH CAPSLLIGLI NMFMFKKRNE GYYDQDGKVY
     RNCHLGYWYP NQRLVETVLI SIAVACIPIM LLGKPLWVRF VTSKRHKLQE TKSLKSIKRN
     GTTVSAPTSP VVETGPPRFV S
//
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