ID   E3Q2T6_COLGM            Unreviewed;       878 AA.
AC   E3Q2T6;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Cullin family protein {ECO:0000313|EMBL:EFQ24915.1};
GN   ORFNames=GLRG_00059 {ECO:0000313|EMBL:EFQ24915.1};
OS   Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS   anthracnose fungus) (Glomerella graminicola).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum graminicola species complex.
OX   NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN   [1] {ECO:0000313|Proteomes:UP000008782}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX   PubMed=22885923; DOI=10.1038/ng.2372;
RA   O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA   Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA   Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA   Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA   Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA   Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA   Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA   Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA   Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA   Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA   van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA   Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA   Ma L.-J., Vaillancourt L.J.;
RT   "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT   by genome and transcriptome analyses.";
RL   Nat. Genet. 44:1060-1065(2012).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG697331; EFQ24915.1; -; Genomic_DNA.
DR   RefSeq; XP_008088935.1; XM_008090744.1.
DR   AlphaFoldDB; E3Q2T6; -.
DR   STRING; 645133.E3Q2T6; -.
DR   EnsemblFungi; EFQ24915; EFQ24915; GLRG_00059.
DR   GeneID; 24405424; -.
DR   VEuPathDB; FungiDB:GLRG_00059; -.
DR   eggNOG; KOG2167; Eukaryota.
DR   HOGENOM; CLU_004747_7_0_1; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000008782; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008782}.
FT   DOMAIN          496..752
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   878 AA;  100237 MW;  D230930140FC9344 CRC64;
     MPSNSPPVVE GALPTRATGR TGGTAALIND TDSPPRRRPR VDSDVSRSST LAPHQQQSTQ
     QSTKPSPKRF KFGADDSSPS HSAMSTKMKG KLPEVIDLTQ SNSYRPYTGA KKLVIKNLRP
     AARNEQLEQY YKRTNQELVD ALQDIFNGGR PRVPLERLYR AVEDICRRGQ DHELELYEIL
     RRNCEEHLAH GVLRSIKFRG GNTDVDMLRS VLQHWRVWNS QIMTIRSTFS FLDRTFLLKE
     KGYPSINDMT ISQFKRMAFP SRDDPNGQSP GGRALRGIYD LMYYDRLGDE RFDAALLKDS
     IMMLHVFNIY TKYFEPRFIE ISEHYFEEFA EERSASSLKE YILACESLLK REDYRCNEYN
     LDSTTKKQLL DAAHGILVKN YSDKLLNVES LSKLLSDYEV DSMKALYDLL RLSGIQKKLK
     EPWSAYIRKT GAIIVADKER GDEMVQRLLE LKRSLGLIVR DAYGGDSDFV NDLRNAFGDF
     MNDRSIAATW TSGTSKVGEM IAKYVDMLLR GGIKALPKAM LSDNKDRAAA EQSGLASAGD
     EDAELDRQLD QALELFRFIQ GKDAFEAFYK KDLARRLLMG RSASQDAERN MLRKLREECG
     MNFTHNLEQM FKDVEVAKEE MEAYKQWSEG TGVDRAPVDL SVMILSAAAW PTYPDVKVHL
     PDDVAKQIER FDQYYKNKHT GRLLNWKHAL AHCTVKAKFP KGTKELLVSA YQAIVLVLFN
     EVGLEGFLTY EQISHSTNLQ GGELVRTLQS LACGQFRVLT KHPKGKDVNP TDTFTINKTF
     VHPKIRLKIN QIQLKETKEE NKATHERIAQ DRRFETQAAI VRIMKSRKEM SHGELVAEVI
     NLTKNRGAVD AAQIKKEIEN LIDKDYLERE GNTYTYLA
//