ID E3QBX9_COLGM Unreviewed; 550 AA.
AC E3QBX9;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=GMC oxidoreductase {ECO:0000313|EMBL:EFQ28214.1};
GN ORFNames=GLRG_03358 {ECO:0000313|EMBL:EFQ28214.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; GG697340; EFQ28214.1; -; Genomic_DNA.
DR RefSeq; XP_008092234.1; XM_008094043.1.
DR AlphaFoldDB; E3QBX9; -.
DR STRING; 645133.E3QBX9; -.
DR EnsemblFungi; EFQ28214; EFQ28214; GLRG_03358.
DR GeneID; 24408723; -.
DR VEuPathDB; FungiDB:GLRG_03358; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_002865_7_1_1; -.
DR OrthoDB; 3714148at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR PANTHER; PTHR11552:SF152; OXIDASE (CODA), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04090)-RELATED; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782}.
FT DOMAIN 264..278
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 93
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 228
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 550 AA; 60926 MW; A3675D0830A65823 CRC64;
MSTTQLPASD VDRYDYVIVG GGTAGCVVAS RLAESLPQKR VLLIEAGPSD FMDDRVLDLR
KWLNLLGGEL DYDYGTTEQP MGNSHIRHSR AKVLGGCSSH NTLISFRPFE YDLKIWQSMG
AKGWTFHDFM RIMDKLRNTV QPVHARHQNE LCLDWVNSCS SALDIPVLHN FNKHITQNGA
LKQGVGFFSI SYNPDDGRRS SASVAYIHPF LRGEEKRPNL TVLTNAWVSK INVRGDTVTG
VNLTLQDGSK RTVTARAETV LCAGAVDTPR LMLLSGIGPK QQLVDLGIPV IHDLPGVGEN
LQDHPESIIM WELKKPVPPN QTTMDSDAGI FLRREPPNAA AKKTFFNPDG IPDGDIADVM
MHCYQIPFTL NTARLGYDEP KDGYAFCMTP NIPRPRSRGR LYLTSADPSV KPALDFRYFT
DEEGYDAATL VYGMRAARKV AEQAPFKDWI AREVAPGPAV QTDEELSLYA RRAAHTVYHP
VGTTKMGDVR KDPLAVVDER LNVKGLKRVR IVDAGIFPTI PTINPMLTVL GVAEKAAEMI
IDEAQETARL
//
