ID E3QIT3_COLGM Unreviewed; 499 AA.
AC E3QIT3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=3-dehydroquinate synthase {ECO:0000313|EMBL:EFQ30771.1};
GN ORFNames=GLRG_05915 {ECO:0000313|EMBL:EFQ30771.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; GG697351; EFQ30771.1; -; Genomic_DNA.
DR RefSeq; XP_008094791.1; XM_008096600.1.
DR AlphaFoldDB; E3QIT3; -.
DR STRING; 645133.E3QIT3; -.
DR EnsemblFungi; EFQ30771; EFQ30771; GLRG_05915.
DR GeneID; 24411280; -.
DR VEuPathDB; FungiDB:GLRG_05915; -.
DR eggNOG; KOG0692; Eukaryota.
DR HOGENOM; CLU_001201_0_4_1; -.
DR OrthoDB; 453at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR CDD; cd08199; EEVS; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR030960; DHQS/DOIS.
DR InterPro; IPR035872; EEVS-like.
DR PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR43622:SF1; 3-DEHYDROQUINATE SYNTHASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01761; DHQ_synthase; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782}.
FT DOMAIN 87..335
FT /note="3-dehydroquinate synthase"
FT /evidence="ECO:0000259|Pfam:PF01761"
FT REGION 431..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 55075 MW; 89483686B6EA1197 CRC64;
MASDMKATVE PTNKGFSVCG YEKIEYDFEF LDGVFNKQNS QLADCYSRWK RCLAVMDLNI
FNLYGKEMKE YFDHYSIELK IHKTMIGEKA KSMETLLSIV DSMTEFGVYR KEPVLVVGGG
LVTDVAGFAC AAYRRNTPFI RIPTTVIGLI DASVSIKVAV NYGNYKNRLG AYHAPTHTFL
DFTFLRTLPT AQIRNGFAEL IKISTCAHLE TFDLLDRFCE ELIKTGFGRC DGASQDVREA
ADKINRNGIH EMLKLETPNL HEIMLDRVIA YGHTWSPLHE LSPDVPLRHG HAISIDMAFS
ATLAHVLGKL SSEEHRRLLN LFSRAGLSMD HPLFDEDMLD KATSAILKTR DGQLRAAVPS
PLGQCVFLND VSHKDMCAAL KVHKDLMKEY PREGAGLEAY VDASDTGYTI NGTSVEDESR
TVLNGVEKVV VSDDTSNGPS SNGSSTPEYG LSNGKNLGRD GAEYAAAGFE SEVTKKLDGG
KEGIKGYGKA QVEVGHECC
//
