ID E3QJG5_COLGM Unreviewed; 885 AA.
AC E3QJG5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=DUF221 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GLRG_06147 {ECO:0000313|EMBL:EFQ31003.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; GG697352; EFQ31003.1; -; Genomic_DNA.
DR RefSeq; XP_008095023.1; XM_008096832.1.
DR AlphaFoldDB; E3QJG5; -.
DR EnsemblFungi; EFQ31003; EFQ31003; GLRG_06147.
DR GeneID; 24411512; -.
DR VEuPathDB; FungiDB:GLRG_06147; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002458_2_1_1; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF26; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 25..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 688..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..181
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 204..395
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 407..679
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 783..877
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 98283 MW; D6609F351D1A2C8B CRC64;
MSGLEDAQSG QDRGEALGDK SGSSISGLVS TLAVCAPIAG VYLVIFLILR RSQRRFYAPR
TYLGSLRESE RSPSLPNGLF NWFGHFWKIP DIYALKHQSL DSYLFLRFLR ICATICLVGL
VMTWPILFPV NATGGGNAGQ LDILSYSNID VTVPSGLNRL YAHALLGWLF YGFVMYLIMR
ECIYYINLRQ AFLLSPTYSK RISSRTVLFT SVPDAYLDEA KFKKLFSDSI KRVWITGDTE
KLDDLVEERD KVAMKLEKAQ VKLIKLANAA RLKAAKKGAL DDKAPTAQDT ESADASARWI
PQKKRPTHRL GPLGLVGKKV DTIEWCRSEL QRLIPAVEAA QAEYRSGKAK KIPAVFAEFF
TQSDAQAAFQ VTTHHQALQM TPKYIGIQPT EVIWKSLRVS WWQRVVRRYA VVAFISALII
FWAVPVTLVG IISQVSYLET VSFLTWLKQI PDVIMGVVSG LLPSVALAVL MSLVPVIMRL
CAKLSGEPSD SRVELFTQNA YFWFQLIQVF LITTISGSAV ATIQAVAQNP GSIFGTLSTA
LPKSSSFYIS YFIVQGITLA TGVLTQVVAF AIFAAVLKFL TNTPRALYQK WSTLAAISWG
SVLPVYTTIA VISISYAIIA PLMLFFSTLG MGLFYLSYRY NVLFVTDTKV DTRGLLYPRA
LKQLFSGVYL AEICMIGLFA VSKAIGPLVL MIVFLVFSVL FHLTLSSVLD PLMYTLPRTL
QVEEESLNAD IEGIDRKDSG RGVSEEQNAD SGNLFKKVPN IKNFAPGGEE NTVGKGGNMV
TRFLKPWISV DYLTLRQLVP HHAATIDEMY PGTIQDNAYF PPSVSSLPPL LWIPEDAAGV
SKSEIAQTSK IIPITDEGCQ LDEKNKLVWD SEAARPPIWD EKIYY
//
