ID E3QL14_COLGM Unreviewed; 2063 AA.
AC E3QL14;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=SH3 domain-containing protein {ECO:0000313|EMBL:EFQ31552.1};
GN ORFNames=GLRG_06841 {ECO:0000313|EMBL:EFQ31552.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR EMBL; GG697356; EFQ31552.1; -; Genomic_DNA.
DR RefSeq; XP_008095572.1; XM_008097381.1.
DR STRING; 645133.E3QL14; -.
DR EnsemblFungi; EFQ31552; EFQ31552; GLRG_06841.
DR GeneID; 24412206; -.
DR VEuPathDB; FungiDB:GLRG_06841; -.
DR eggNOG; KOG1998; Eukaryota.
DR HOGENOM; CLU_000595_0_1_1; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08679; C2_DOCK180_related; 1.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 7..87
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 629..811
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1461..1871
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 90..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1792..1816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1866..1904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1930..2016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1796..1810
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1870..1904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1934..1956
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1963..2010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2063 AA; 228820 MW; D15E85C0DFD97D38 CRC64;
MPWQPLPRIA FAVATYPFAA SGPADLPLEL GDELYIIEET PDGNWLRGYL VAPPSLLAGL
TSVKGQTLEA RVFSGIFPRS CVEVREVLGE ADDTDDADDA ASDDATADTH FGSDSAKSGL
TRTAIDIPKA IQRHKSFGNA KGPRGNRTGT KGRTPLQELP NGTHGRLSIP VKRDPDAPRP
AAPVPMLKIG DETPTSAAEP LIDEIASCLR EWHSTNLHGL LLSRQYSRLE KLSQLIHTLN
LSRQQFLHNV LTRHEYQRLR EKTVWDLVRV NKLCGGEVVV RDPADRGRVL TGDDSVVDIT
KLQSVMSVLD EPPQPTVEPT ALHHLLFDVK GFAGASAEET SLAAYLVAKP VGGKVTTLTE
CFIIEIPPGG TIGSLAKSGQ TRTVFADLSS QDIGDGASAD TELYLVVKVR SSEQIIASRK
PDSRSGAKSQ GTGYSKDPTK PTSAGNGKPS RRSLMWGSKS GRSAFSRGNA TPKLDSLTEY
PEARPSTQDD GQGSAPPPST DGSRPRGSFD AGAGFLMAER TVGVGVLKLN SIMKQDDDVE
QVVSIWSASL TPPAEKQSLN DEWDGLIRDL MDSKSGHYEK SRRTERVQVH LRSFNHPDVD
ELVKTTPTLL AGIRKTNKLG FSGAPTKARS DIYVTLDSAA LSKHNLLSRY AGSPTTLASS
VQGNHLQVML EVRRSDGEKI PNCIFSSSNT EGITTWKSVA VERGDHWSQT VRLAISPEDV
FTSHLVMFLS DMPNPPFAVA HMPLWNQEAF VRDGTHALLL YKADEFTSTA QAGPSGRGGY
LSLQWSARGN EEHSADVTGP QAILRVDTYL CSTRFSQDRV VLGLLKWKEA AKDDIPTLLK
HLIFVPEIEV VKLLSDVLDA LFGVLVEYSG NDELEDLVFT ALVRVLGIVH DRRFNLGPLV
DHYAENRFNY PFATACLVRS FTRLLEKPAE PTTSRKLRST FKVVRHILKF ITHARGQQQA
KEAGIGITHS HSAPGFTREL RNIFKALDAM MRSHAPVLVG SQTLAVQHFH TWLPELTGLL
STEEILHIAI DFLDSCADVK GKLVLYKLVL IINYSKLDIF SHPDQKSALT ANTVRWIAPH
WGHTEAVTDS WKEQVRLCCS VLAGQIDNLG PEIPDYLPKI IDSYMSIVAV PTKPRNRLSL
LFPTSYPFPC KPVTEKCTFD EALVELSAIL SAVSNSPSGM QLELIEGDLT LLLENTLRVH
MSILMGEAFP PDWLSVHIYH HKSTMKTLQY LSSILLESYL PHPDDAENFN TELWKMFFTT
MLKLVGSPSL ALETFPEQKR RAVWKIAGDV REHGAELLRR TWEAIGWETS ADERDRYKLS
KMGGYQVQYV PTLVGPIVEL CLSVHQGLRR MAVEVLQTMI VSEWTLSEDL SVIQTEIIDS
LDQYFKSKPL TESILQKLFI GEVLERFAPL ATGPDEALHA AICELMGTVN EFLDLLVAVH
SSDNTSEASH LINRLRLMEF LRDMQKEEIF IRYVHQLAAL QAEARNHCEA GLALRLHADL
YDWDPTKQVP ALSEPEFPVQ TSFERKERIY FDMIKHFEDG EAWSSALAAY RELRTQYESN
VFDFAKLART ERAIATVYET ISRSDRLIPK YFKVVYKGLG FPSSLRDKEF VYEGSPTERA
SAFTDRMQEL YPSAQIVTGG DVDDVEGQFL VVSAITPHRD LTHQVFQRAR VPQVIRDYLL
SANPQSFSVS SKRDTSGPVK EHHAEKIVFT TADPFPTILR RSEIVYTEDI KLGARETGLE
RIVRKTQEMT VIEKRVAEGD EENAQLLVDA VSVSVNPGSD NSVACYRQLL PAASSDDDNG
DDDDEEQETR LDPQDNAIKM ALVDHAIMIK RCLATFAKSS NEVLNRRHEE LRQYFESTFA
PEIALFAPQQ PTRDFTNIQP WRRSSPSTEQ GSPQPQSTTG ATDNVVVAEE VSTVQPIAIR
QGRGTRLSFL GGRKRQSPVQ QQTNSNSSAS GDADDTLSQH SRSRSRAQDT SSRLSFFRAP
STDGGRMNGS NDAASEWVTD SGGRQSSDTG FNLTEKEREY RDESLADDPI VIKRSSVRKR
LSMLKLGKKS HKHGGVMGSV HEE
//
